Himed Sonia, Gray Ashley, Awethe Zaynah, Libson Karissa, Kaffenberger Benjamin H, Korman Abraham M, Trinidad John C L
College of Medicine, University of Cincinnati, Cincinnati, OH USA.
Division of Dermatology, Department of Internal Medicine, The Ohio State University, Columbus, OH USA.
Curr Dermatol Rep. 2022;11(4):252-262. doi: 10.1007/s13671-022-00374-5. Epub 2022 Oct 19.
The overall purpose of this review was to characterize and summarize cutaneous eruptions associated with coronavirus disease 2019 (COVID-19) as well as COVID-19 vaccination.
Cutaneous eruptions associated with COVID-19 infection have a reported frequency of 1-20%. Increased COVID-19 disease severity has been associated with morbilliform exanthems, urticaria, retiform purpura, and livedo racemosa. Papulovesicular eruptions were associated with a milder COVID-19 disease course. A range of dermatoses have also been reported with COVID-19 vaccination but have rarely prevented subsequent vaccination.
Dermatologists should be aware of the associations between COVID-19 disease severity and cutaneous eruptions. Livedo racemosa and retiform purpura are particularly associated with increased disease severity and death. In the setting of COVID-19 vaccination, cutaneous eruptions can largely be managed symptomatically and very rarely do these reactions prevent subsequent vaccination.
本综述的总体目的是描述和总结与2019冠状病毒病（COVID-19）以及COVID-19疫苗接种相关的皮肤疹。
据报道，与COVID-19感染相关的皮肤疹出现频率为1%-20%。COVID-19疾病严重程度增加与麻疹样皮疹、荨麻疹、网状紫癜和匐行性回状红斑有关。丘疹水疱性皮疹与较轻的COVID-19病程有关。也有一系列皮肤病与COVID-19疫苗接种相关，但很少会导致后续疫苗接种无法进行。
皮肤科医生应了解COVID-19疾病严重程度与皮肤疹之间的关联。匐行性回状红斑和网状紫癜尤其与疾病严重程度增加和死亡有关。在COVID-19疫苗接种的情况下，皮肤疹大多可进行对症处理，这些反应很少会导致后续疫苗接种无法进行。
