Bombieri Filippo Federico, Shafafy Roozbeh, Elsayed Sherief
Medicine & Surgery, Furness General Hospital, University Hospitals of Morecambe Bay NHS Foundation Trust, Kendal, UK.
Spinal Deformity Unit, Royal National Orthopaedic Hospital, London, UK.
J Spine Surg. 2022 Sep;8(3):377-389. doi: 10.21037/jss-21-59.
Open discectomy (OD) and microdiscectomy (MD) are routine procedures for the treatment of lumbar disc herniation. Minimally invasive surgery (MIS), such as micro-endoscopic discectomy (MED) and full endoscopic discectomy (FED), offers potential advantages (less pain, less bleeding, shorter hospitalisation and earlier return to work), but their complications have not yet been fully evaluated. The aim of this paper was to identify the frequency of these complications with a focus on MIS in comparison to OD/MD.
The authors conducted a Medline database search for randomised controlled and prospective cohort studies reporting complications associated with MIS and MD/OD from 1997 to February 2020. Included studies were assessed for bias using the Newcastle-Ottawa Quality assessment form. Mean complication rates for each technique were calculated by dividing the total number of each complication by the total number of patients included in the studies which reported that specific complication.
Of the 1,095 articles retrieved from Medline, 35 met the inclusion criteria. OD, MD, MED and FED were associated with: recurrent lumbar disc hernias in 4.1%, 5.1%, 3.9% and 3.5% respectively; re-operations in 5.2%, 7.5%, 4.9% and 4% respectively; wound complications in 3.5%, 3.5%, 1.2% and 2% respectively; durotomy in 6.6%, 2.3%, 4.4% and 1.1% respectively; neurological complications in 1.8%, 2.8%, 4.5% and 4.9% respectively. Nerve root injury was reported in 0.3% for MD, 0.8% for MED and 1.2% for FED.
This up-to-date systematic review of complications after various techniques of lumbar discectomy (including a large pool of patients who had MIS) confirms previous findings of low and comparable rates. However variable levels of bias were reported amongst included studies, which reported complications with varying levels of clinical detail.
开放式椎间盘切除术(OD)和显微椎间盘切除术(MD)是治疗腰椎间盘突出症的常规手术。微创外科手术(MIS),如显微内镜下椎间盘切除术(MED)和全内镜下椎间盘切除术(FED),具有潜在优势(疼痛减轻、出血减少、住院时间缩短和更早重返工作岗位),但其并发症尚未得到充分评估。本文旨在确定这些并发症的发生率,并重点关注与OD/MD相比的MIS。
作者对Medline数据库进行了检索,以查找1997年至2020年2月期间报告与MIS以及MD/OD相关并发症的随机对照和前瞻性队列研究。使用纽卡斯尔-渥太华质量评估表对纳入研究的偏倚进行评估。通过将每种并发症的总数除以报告该特定并发症的研究中纳入的患者总数,计算每种技术的平均并发症发生率。
从Medline检索到的1095篇文章中,35篇符合纳入标准。OD、MD、MED和FED分别与以下情况相关:复发性腰椎间盘突出症的发生率分别为4.1%、5.1%、3.9%和3.5%;再次手术的发生率分别为5.2%、7.5%、4.9%和4%;伤口并发症的发生率分别为3.5%、3.5%、1.2%和2%;硬脊膜切开术的发生率分别为6.6%、2.3%、4.4%和1.1%;神经并发症的发生率分别为1.8%、2.8%、4.5%和4.9%。MD的神经根损伤报告率为0.3%,MED为0.8%,FED为1.2%。
这项对各种腰椎间盘切除技术(包括大量接受MIS的患者)术后并发症的最新系统评价证实了先前低且可比发生率的研究结果。然而,纳入研究报告了不同程度的偏倚,且对并发症的临床细节报告程度各异。