Rossitto Christina P, Devarajan Alex, Price Gabrielle, Ali Muhammad, Kellner Christopher P
Department of Neurosurgery, Icahn School of Medicine, 1468 Madison Avenue, Annenberg Building, 8th Floor, New York, NY 10029, USA.
Methods Protoc. 2022 Oct 9;5(5):80. doi: 10.3390/mps5050080.
Cranioplasty is a neurosurgical procedure in which the skull bone is repaired after craniectomy. Recently, studies have suggested that sonolucent synthetic materials are safe and useful for cranioplasty. Sonolucent cranioplasty (SC) implants provide unprecedented opportunity in adult neurosurgery to monitor neuroanatomy, assess hemodynamics, view devices located within the implant, and conduct focused ultrasound treatments. Current research on SC includes proof-of-concept cadaveric studies, patient-related safety and feasibility studies, and case series demonstrating transcranioplasty ultrasonography (TCUS). The purpose of this protocol is to investigate the current literature on SC use and outcomes in TCUS. We will perform a systematic literature search following PRISMA-ScR guidelines. The search will be conducted using Ovid Embase, Ovid Medline, and Web of Science Core Collection databases. Titles, abstracts, and full texts will be screened. Joanna Briggs Institute critical appraisal tools will be utilized. Data extraction points will include subject characteristics, SC implant characteristics, ultrasound characteristics, and sonographic findings. These findings will provide a comprehensive review of the literature on sonolucent cranioplasty and directions for future research.
颅骨修补术是一种神经外科手术，即在颅骨切除术后修复颅骨。最近，研究表明，透声合成材料在颅骨修补术中是安全且有用的。透声颅骨修补术（SC）植入物为成人神经外科手术提供了前所未有的机会，可用于监测神经解剖结构、评估血流动力学、查看植入物内的装置以及进行聚焦超声治疗。目前关于SC的研究包括概念验证尸体研究、与患者相关的安全性和可行性研究，以及展示经颅骨修补术超声检查（TCUS）的病例系列。本方案的目的是调查目前关于SC在TCUS中的应用和结果的文献。我们将按照PRISMA-ScR指南进行系统的文献检索。检索将使用Ovid Embase、Ovid Medline和Web of Science核心合集数据库进行。将筛选标题、摘要和全文。将使用乔安娜·布里格斯研究所的批判性评价工具。数据提取点将包括受试者特征、SC植入物特征、超声特征和超声检查结果。这些发现将对透声颅骨修补术的文献进行全面综述，并为未来的研究指明方向。
