Yum M, Wheat L J, Maxwell D, Edwards J L
Am J Clin Pathol. 1978 Nov;70(5):832-5. doi: 10.1093/ajcp/70.5.832.
A 75-year-old man with Staphylococcus aureus endocarditis in whom acute diffuse proliferative glomerulonephritis developed is described. The light- and electron-microscopic changes of the glomeruli in this case were identical to those of acute poststreptococcal glomerulonephritis. Immunofluorescence revealed deposition of immunoglobulins and complement in the glomeruli. In addition, bacterial antigenic material was demonstrated in the glomeruli by indirect immunofluorescence. These observations further support the hypothesis of an immune-complex pathogenesis in this form of glomerulonephritis.
本文描述了一名75岁患金黄色葡萄球菌性心内膜炎并发生急性弥漫性增生性肾小球肾炎的男性患者。该病例肾小球的光镜和电镜变化与急性链球菌感染后肾小球肾炎相同。免疫荧光显示肾小球中有免疫球蛋白和补体沉积。此外，通过间接免疫荧光在肾小球中证实了细菌抗原物质。这些观察结果进一步支持了这种形式的肾小球肾炎免疫复合物发病机制的假说。
