Alves João C, Santos Ana, Jorge Patrícia, Lavrador Catarina, Carreira Luís Miguel
Divisão de Medicina Veterinária, Guarda Nacional Republicana (GNR), Rua Presidente Arriaga, 9, 1200-771 Lisbon, Portugal.
MED-Mediterranean Institute for Agriculture, Environment and Development, Instituto de Investigação e Formação Avançada, Universidade de Évora, Pólo da Mitra, Ap. 94, 7006-554 Evora, Portugal.
Animals (Basel). 2022 Oct 17;12(20):2808. doi: 10.3390/ani12202808.
Osteoarthritis (OA) is the most commonly diagnosed joint disease in companion animals, and proper tools are necessary to assess patients and response to treatment. We aimed to perform the psychometric evaluation of several clinical metrology instruments (CMI), developed to evaluate pain and assess outcome. Fifty police working dogs with bilateral hip OA were assessed in a prospective, randomised, double-blinded study. Patients were evaluated using a stance analyser in six different moments divided over a 180-day period. Pedometer step count, weight-bearing symmetry index and deviation from normal weight-bearing were calculated and used for criterion validity. In each evaluation moment, a copy of the Hudson Visual Analogue Scale (HVAS), Canine Brief Pain Inventory (CBPI), Liverpool Osteoarthritis in Dogs (LOAD) and Canine Orthopaedic Index (COI) were completed by the dogs' handlers. Correlations between CMIs were evaluated as construct validity. Further evaluation was performed with the Kaiser-Meyer-Olin measure of sampling adequacy, Eigenvalue and scree-plot analysis. Internal consistency was tested with Cronbach's α. Significant weak correlation was found between all CMIs and stance analysis symmetry index measure and deviation, indicating criterion validity. Significant weak correlation was also found between pedometer count and LOAD plus COI. Cronbach's α was 0.80 for HVAS, 0.98 for CBPI, 0.97 for LOAD and 0.98 for COI. Significant strong correlation was observed between CMIs, indicating construct validity. We present criterion and construct validity of these CMIs, which are able to capture various dimensions of OA. They can be used for the evaluation of osteoarthritis and response to treatment in dogs.
骨关节炎（OA）是伴侣动物中最常被诊断出的关节疾病，因此需要合适的工具来评估患者及其对治疗的反应。我们旨在对几种临床计量仪器（CMI）进行心理测量评估，这些仪器是为评估疼痛和治疗结果而开发的。在一项前瞻性、随机、双盲研究中，对50只患有双侧髋关节OA的警犬进行了评估。在180天的时间内，分六个不同时刻使用姿态分析仪对患者进行评估。计算计步器步数、负重对称指数和与正常负重的偏差，并将其用于效标效度评估。在每个评估时刻，由犬只的训导员完成一份哈德逊视觉模拟量表（HVAS）、犬简短疼痛量表（CBPI）、犬类利物浦骨关节炎量表（LOAD）和犬类骨科指数（COI）。评估CMI之间的相关性作为结构效度。使用凯泽-迈耶-奥林抽样适当性度量、特征值和碎石图分析进行进一步评估。使用克朗巴哈α系数测试内部一致性。发现所有CMI与姿态分析对称指数测量值和偏差之间存在显著弱相关性，表明效标效度。在计步器计数与LOAD加COI之间也发现了显著弱相关性。HVAS的克朗巴哈α系数为0.80，CBPI为0.98，LOAD为0.97，COI为0.98。在CMI之间观察到显著强相关性，表明结构效度。我们展示了这些CMI的效标效度和结构效度，它们能够捕捉OA的各个维度。它们可用于评估犬类骨关节炎及对治疗的反应。
