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辅酶Q作为食品补充剂在纤维肌痛管理中的应用:一项批判性综述。

The Use of the Coenzyme Q as a Food Supplement in the Management of Fibromyalgia: A Critical Review.

作者信息

Campisi Luca, La Motta Concettina

机构信息

Department of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.

出版信息

Antioxidants (Basel). 2022 Sep 30;11(10):1969. doi: 10.3390/antiox11101969.

DOI:10.3390/antiox11101969
PMID:36290691
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9598746/
Abstract

The coenzyme Q is a naturally occurring benzoquinone derivative widely prescribed as a food supplement for different physical conditions and pathologies. This review aims to sum up the key structural and functional characteristics of Q, taking stock of its use in people affected by fibromyalgia. A thorough survey has been conducted, using Pubmed, Scifinder, and ClinicalTrials.gov as the reference research applications and registry database, respectively. Original articles, reviews, and editorials published within the last 15 years, as well as open clinical investigations in the field, if any, were analyzed to point out the lights and shadows of this kind of supplementation as they emerge from the literature.

摘要

辅酶Q是一种天然存在的苯醌衍生物,作为食品补充剂被广泛用于不同的身体状况和病症。本综述旨在总结辅酶Q的关键结构和功能特征,并评估其在纤维肌痛患者中的应用情况。我们分别使用PubMed、Scifinder和ClinicalTrials.gov作为参考研究应用程序和注册数据库进行了全面的调查。分析了过去15年内发表的原创文章、综述和社论,以及该领域的公开临床研究(如有),以指出文献中出现的这种补充剂的优缺点。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a9/9598746/b8bd749541da/antioxidants-11-01969-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a9/9598746/d588d226787a/antioxidants-11-01969-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a9/9598746/b8bd749541da/antioxidants-11-01969-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a9/9598746/d588d226787a/antioxidants-11-01969-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/48a9/9598746/b8bd749541da/antioxidants-11-01969-g002.jpg

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2
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J Clin Med. 2022 Apr 27;11(9):2462. doi: 10.3390/jcm11092462.
3
Nutritional Supplementation With Coenzyme Q10, Tryptophan and Magnesium in Fibromyalgia Treatment: A Letter to Editor.辅酶Q10、色氨酸和镁在纤维肌痛治疗中的营养补充:致编辑的一封信
线粒体功能障碍与辅酶 Q10 在病毒性疲劳综合征中的补充:概述。
Int J Mol Sci. 2024 Jan 1;25(1):574. doi: 10.3390/ijms25010574.
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Effect of ubiquinol on cardiorespiratory fitness during high-altitude acclimatization and de-acclimatization in healthy adults: the Shigatse CARdiorespiratory fitness study design.泛醇对健康成年人在高原适应和脱适应过程中心肺适能的影响:日喀则心肺适能研究设计
Front Cardiovasc Med. 2023 Jul 25;10:1129144. doi: 10.3389/fcvm.2023.1129144. eCollection 2023.
Reumatol Clin (Engl Ed). 2022 Jan;18(1):62-63. doi: 10.1016/j.reumae.2020.04.016.
4
The Role of Nutrient Supplementation in the Management of Chronic Pain in Fibromyalgia: A Narrative Review.营养补充在纤维肌痛慢性疼痛管理中的作用:一项叙述性综述。
Pain Ther. 2021 Dec;10(2):827-848. doi: 10.1007/s40122-021-00266-9. Epub 2021 Apr 28.
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