Zhu Chenxi, Liu Guoxing, Gu Xiankun, Zhang Tongqing, Xia Aijun, Zheng You, Yin Jiawen, Han Mingming, Jiang Qichen
Freshwater Fisheries Research Institute of Jiangsu Province, Nanjing 210017, China.
Geography Section, School of Humanities, Universiti Sains Malaysia, Minden 11800, Malaysia.
Antioxidants (Basel). 2022 Oct 12;11(10):2015. doi: 10.3390/antiox11102015.
Flavonoids have antimicrobial and anti-oxidation properties. The effects of the flavonoid quercetin on the intestinal microflora of freshwater dark sleeper were tested for the first time. juveniles were treated with quercetin for 21 days at one of three concentrations (2.5, 5.0, or 10.0 mg/L) and compared with a control group that was not treated with quercetin. Quercetin improved the stability of the intestinal flora in and the probiotic bacteria spp. and spp. increased in species abundance after the low concentration quercetin treatments. Furthermore, the abundance of pathogenic bacteria spp., spp., and spp. decreased after the fish had been exposed to quercetin. Activity of hepatic antioxidant enzymes (superoxide dismutase, SOD), (glutathione S-transferase, GST), (glutathione peroxidase, GSH-Px), and (total antioxidant capacity, T-AOC) increased in the livers of treated with quercetin, thereby increasing their hepatic antioxidant capacity and their ability to scavenge free radicals.
类黄酮具有抗菌和抗氧化特性。首次测试了类黄酮槲皮素对淡水暗纹东方鲀肠道微生物群的影响。将幼鱼用三种浓度（2.5、5.0或10.0毫克/升）之一的槲皮素处理21天，并与未用槲皮素处理的对照组进行比较。槲皮素改善了肠道菌群的稳定性，低浓度槲皮素处理后益生菌嗜水气单胞菌属和芽孢杆菌属的物种丰度增加。此外，在鱼接触槲皮素后，病原菌肠杆菌属、葡萄球菌属和弧菌属的丰度降低。用槲皮素处理的淡水暗纹东方鲀肝脏中肝抗氧化酶（超氧化物歧化酶，SOD）、（谷胱甘肽S-转移酶，GST）、（谷胱甘肽过氧化物酶，GSH-Px）和（总抗氧化能力，T-AOC）的活性增加，从而提高了它们的肝脏抗氧化能力和清除自由基的能力。
