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β-肾上腺素能受体阻断药、心率与大鼠遗传性高血压的发展

Beta-adrenoceptor blocking drugs, heart rate and genetic hypertension development in rats.

作者信息

Richer C, Venturini-Souto N, Giudicelli J F

出版信息

Experientia. 1979 May 15;35(5):656-7. doi: 10.1007/BF01960381.

DOI:10.1007/BF01960381
PMID:36293
Abstract

In spontaneously hypertensive rats (SHRs) chronically treated during their growth with beta-adrenoceptor blocking drugs, no correlation was found between the reduction in heart rate and the prevention of genetic hypertension development.

摘要

在生长过程中用β-肾上腺素能受体阻断药物进行长期治疗的自发性高血压大鼠(SHRs)中,未发现心率降低与遗传性高血压发展的预防之间存在相关性。

相似文献

1
Beta-adrenoceptor blocking drugs, heart rate and genetic hypertension development in rats.β-肾上腺素能受体阻断药、心率与大鼠遗传性高血压的发展
Experientia. 1979 May 15;35(5):656-7. doi: 10.1007/BF01960381.
2
Comparison of the anti-hypertensive response to beta-adrenoceptor blocking drugs in intact and adrenal-demedullated spontaneously hypertensive rats.完整的和肾上腺髓质切除的自发性高血压大鼠对β-肾上腺素能受体阻断药物的抗高血压反应比较。
Br J Pharmacol. 1980 Apr;68(4):667-76. doi: 10.1111/j.1476-5381.1980.tb10859.x.
3
[Antihypertensive effect of arotinolol (S-596), a new adrenergic beta blocking agent, on experimental hypertension].新型肾上腺素β受体阻滞剂阿罗洛尔(S-596)对实验性高血压的降压作用
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Beta-adrenergic receptor blocking drugs in spontaneous hypertension.β-肾上腺素能受体阻断药与自发性高血压
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Pressor effects of orally administered beta-adrenergic receptor blocking agents in consciou spontaneously hypertensive rats.口服β-肾上腺素能受体阻滞剂对清醒自发性高血压大鼠的升压作用。
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Acute hypotensive effect of combined beta1-adrenoceptor blockade and beta2-adrenoceptor stimulation in spontaneously hypertensive rats (SHR).β1肾上腺素能受体阻断与β2肾上腺素能受体刺激联合应用对自发性高血压大鼠(SHR)的急性降压作用
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A further study on antihypertensive action of beta-adrenoceptor blocking agents in conscious, renal hypertensive dogs.β-肾上腺素能受体阻滞剂对清醒肾性高血压犬降压作用的进一步研究。
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Development of SHR hypertension and cardiac hypertrophy during prolonged beta blockade.在长期β受体阻滞剂治疗期间SHR高血压和心脏肥大的发展
Am J Physiol. 1977 Jun;232(6):H639-644. doi: 10.1152/ajpheart.1977.232.6.H639.
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[Effect of acebutolol, a cardioselective beta-adrenoceptor blocking agent, on the blood pressure in rats (author's transl)].心脏选择性β-肾上腺素能受体阻滞剂醋丁洛尔对大鼠血压的影响(作者译)
Nihon Yakurigaku Zasshi. 1979 Oct;75(7):747-54.

本文引用的文献

1
Effects of prolonged treatment with adrenergic beta-receptor antagonists on blood pressure, cardiovascular design and reactivity in spontaneously hypertensive rats (SHR).肾上腺素能β受体拮抗剂长期治疗对自发性高血压大鼠(SHR)血压、心血管结构及反应性的影响。
Acta Physiol Scand. 1974 Aug;91(4):447-57. doi: 10.1111/j.1748-1716.1974.tb05701.x.
2
Pharmacokinetics of M&B 17,803A in animals and man.M&B 17,803A在动物和人体中的药代动力学。
Br J Pharmacol. 1973 Mar;47(3):620P.
3
Chronic atenolol treatment and hypertension development in spontaneously hypertensive rats.
阿替洛尔长期治疗与自发性高血压大鼠高血压的发展
Eur J Pharmacol. 1978 Feb 15;47(4):393-400. doi: 10.1016/0014-2999(78)90119-x.
4
Sympathetic nerve activity: role in regulation of blood pressure in the spontaenously hypertensive rat.交感神经活动:在自发性高血压大鼠血压调节中的作用
Circ Res. 1976 Jun;38(6 Suppl 2):21-9. doi: 10.1161/01.res.38.6.21.
5
[Anti-hypertensive action of tenormine in the genetically hypertensive rat].[心得安对遗传性高血压大鼠的降压作用]
Nouv Presse Med. 1975 May 31;4(22):1661.