Venkatesh Ramesh, Agrawal Sameeksha, Reddy Nikitha Gurram, Mangla Rubble, Yadav Naresh Kumar, Chhablani Jay
Narayana Nethralaya, Department of Retina and Vitreous, #121/C, Chord Road, 1st R Block Rajaji Nagar, Bangalore 560010, India.
Medical Retina and Vitreoretinal Surgery, University of Pittsburgh School of Medicine, 203 Lothrop Street, Suite 800, Pittsburg, PA 15213, USA.
J Clin Med. 2022 Oct 11;11(20):5983. doi: 10.3390/jcm11205983.
We report on a case series that revealed flat, choroidal lesions on optical coherence tomography (OCT) and on enface MultiColor (MCI) imaging of the fundus but were not noticeable on clinical examination or conventional color fundus images. This observational study included 12 eyes from 11 patients who had distinct, orange-colored lesions on MCI. Retinal imaging was conducted using conventional color fundus photography and OCT. On the color fundus images and the blue and green reflectance channels of MCI, each of the lesions was difficult to distinguish. On the infrared channel, the lesion was identified as bright white in color and bright orange on the multicolor image. The lesion was identified on OCT as a flat, homogeneous hyperreflective lesion involving the choroid, with an intact overlying retinal pigment epithelium and retinal layers. A comparison of the clinical and imaging features with other known entities led to the conclusion that the lesion was a distinct clinical entity. The presence of melanin in the lesion was confirmed based on the retinal imaging findings and the light absorption properties of melanin. As a result, the lesion was named as 'choroidal melanocytic hamartoma'. A longer follow-up is required to confirm the benign nature of this clinical entity.
我们报告了一系列病例，这些病例在光学相干断层扫描（OCT）和眼底正面多色（MCI）成像中显示为扁平的脉络膜病变，但在临床检查或传统彩色眼底图像上并不明显。这项观察性研究纳入了11例患者的12只眼，这些患者在MCI上有明显的橙色病变。使用传统彩色眼底摄影和OCT进行视网膜成像。在彩色眼底图像以及MCI的蓝色和绿色反射通道上，每个病变都难以区分。在红外通道上，病变显示为亮白色，在多色图像上为亮橙色。在OCT上，病变被识别为累及脉络膜的扁平、均匀高反射性病变，其上视网膜色素上皮和视网膜层完整。将临床和影像学特征与其他已知病变进行比较后得出结论，该病变是一种独特的临床实体。根据视网膜成像结果和黑色素的光吸收特性，证实病变中存在黑色素。因此，该病变被命名为“脉络膜黑素细胞错构瘤”。需要更长时间的随访来证实这一临床实体的良性性质。
