Venkatesh Ramesh, Bavaharan Bharathi, Yadav Naresh Kumar, Saurabh Kumar, Srinivasan Priya, Mahendradas Padmalini, Prabhu Vishma, Roy Rupak
1Department of Retina and Vitreous, Narayana Nethralaya, #121/C, 1st R Block, Chord Road, Rajaji Nagar, Bengaluru, Karnataka 560010 India.
Department of Retina and Vitreous, Aditya Birla Sankara Nethralaya, No. 147, Mukundapur EM By Pass, Near Purva Jadavpur Thana, Kolkata, West Bengal 700099 India.
Int J Retina Vitreous. 2018 Dec 13;4:46. doi: 10.1186/s40942-018-0150-y. eCollection 2018.
To describe the multicolour (MC) imaging characteristics associated with choroidal osteomas (CO) and their secondary complications.
Retrospective descriptive case series of eleven eyes of ten patients with CO. Findings of multicolour imaging were correlated with visual acuity, clinical features, lesion characteristics and findings from other imaging modalities.
Infrared reflectance (IR) images showed calcified CO lesions as hyporeflectance (dark) areas while decalcified lesions were seen as iso reflectance (normal) areas. Overlying RPE atrophy on IR were seen as white areas. MC images showed color variations depending upon the reflectivity of the tumour material tumour and retinal pigment epithelial (RPE) atrophy. Green color was noted in calcified CO tumour while decalcified CO tumour showed no color change. RPE atrophy were seen as bright orange areas. Green and blue reflectance images were not able to pick the choroidal osteoma lesion. Other changes secondary to CO like presence of choroidal neovascular membrane, hemorrhage and/or fluid in the retinal layers were identified on green and blue reflectance images.
MC imaging is a useful tool in our arsenal of existing imaging modalities in the assessment of CO and its secondary changes. Change in reflectance of the IR and MC images can be used as an indicator to assess the extent of tumour decalcification and its secondary changes and therefore, can aid in prognostication in the same. It has the potential to replace color fundus photography in documentation and follow up of patients with CO.
描述与脉络膜骨瘤（CO）及其继发并发症相关的多色（MC）成像特征。
对10例患有CO的患者的11只眼进行回顾性描述性病例系列研究。多色成像的结果与视力、临床特征、病变特征以及其他成像方式的结果相关联。
红外反射（IR）图像显示钙化的CO病变为低反射（暗）区域，而脱钙病变则表现为等反射（正常）区域。IR图像上覆盖的视网膜色素上皮（RPE）萎缩表现为白色区域。MC图像显示颜色变化取决于肿瘤物质的反射率以及肿瘤和视网膜色素上皮（RPE）萎缩情况。钙化的CO肿瘤呈现绿色，而脱钙的CO肿瘤无颜色变化。RPE萎缩表现为亮橙色区域。绿色和蓝色反射图像无法检测到脉络膜骨瘤病变。在绿色和蓝色反射图像上可识别出CO继发的其他变化，如脉络膜新生血管膜的存在、视网膜层内的出血和/或积液。
MC成像在我们现有的成像方式中是评估CO及其继发变化的有用工具。IR和MC图像反射率的变化可作为评估肿瘤脱钙程度及其继发变化的指标，因此有助于对其进行预后评估。它有潜力在CO患者的记录和随访中取代彩色眼底照相。
