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镰状细胞病患者的拔牙率

Rate of Dental Extractions in Patients with Sickle Cell Disease.

作者信息

Ahmad Adeel, Mihalca Diana, Stacey Ben, Samaee Sayna, Mehta Dipal, Hibbs Stephen, Freeman Tanya, Chatterjee Basabi, Ali Enamul, Cheng Leo, Tsitsikas Dimitris A

机构信息

Haemoglobinopathy Service, Department of Haematology, Homerton University Hospital NHS Foundation Trust, London E9 6SR, UK.

Department of Oral & Maxillofacial, Head & Neck Surgery, Homerton University Hospital NHS Foundation Trust, London E9 6SR, UK.

出版信息

J Clin Med. 2022 Oct 19;11(20):6174. doi: 10.3390/jcm11206174.

Abstract

BACKGROUND

Sickle cell disease is an inherited disorder associated with chronic haemolysis and anaemia, recurrent episodes of pain and potentially multisystem end-organ damage. A lot less is known about the dental health of these patients.

AIMS

To explore the incidence of severe dental disease leading to dental extraction in our sickle cell population.

PATIENT/METHODS: We undertook an audit looking at the rate of dental extractions, as a composite marker of severe dental disease, among sickle cell patients over a 3-month period. The patients were unselected and approached during routine assessments. We analysed both clinical and laboratory data to look for possible associations between dental disease and sickle cell characteristics.

RESULTS

177 patients were interviewed between February 2022 and April 2022. Overall, 71% of the patients had at least one dental extraction with a median number of teeth extracted of three and a median age at first extraction of 26. More than half of the patients stated that they do not have regular dental check-ups. There were no significant associations with the severity of sickle cell phenotype, baseline Hb or markers of haemolysis.

CONCLUSION

A large number of patients with sickle cell disease require dental extractions at a relatively young age. The lack of any correlation with disease severity suggests that poor engagement with dental services and the underestimation of the importance of dental health are the main factors behind the increased prevalence of severe dental disease. Actively enquiring about dental problems should be part of any routine consultation with these patients, both in primary and specialist care.

摘要

背景

镰状细胞病是一种遗传性疾病,与慢性溶血和贫血、反复发作的疼痛以及潜在的多系统终末器官损伤有关。人们对这些患者的口腔健康了解甚少。

目的

探讨导致我们镰状细胞病患者群体拔牙的严重口腔疾病的发生率。

患者/方法:我们进行了一项审计,观察镰状细胞病患者在3个月期间拔牙率这一严重口腔疾病的综合指标。患者未经挑选,在常规评估期间接受调查。我们分析了临床和实验室数据,以寻找口腔疾病与镰状细胞特征之间可能的关联。

结果

在2022年2月至2022年4月期间,对177名患者进行了访谈。总体而言,71%的患者至少拔过一次牙,拔牙中位数为3颗,首次拔牙的中位年龄为26岁。超过一半的患者表示他们没有定期进行口腔检查。镰状细胞表型的严重程度、基线血红蛋白或溶血标志物之间无显著关联。

结论

大量镰状细胞病患者在相对年轻时就需要拔牙。与疾病严重程度缺乏任何相关性表明,对口腔服务的参与度低以及对口腔健康重要性的低估是严重口腔疾病患病率增加的主要因素。在基层医疗和专科医疗中,主动询问这些患者的口腔问题应成为任何常规会诊的一部分。

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