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重型β地中海贫血和镰状细胞贫血患者的口腔及牙周健康状况:一项对比研究。

Dental and periodontal health status of Beta thalassemia major and sickle cell anemic patients: a comparative study.

作者信息

Singh Jaideep, Singh Nitin, Kumar Amit, Kedia Neal Bharat, Agarwal Anil

机构信息

Department of Orthodontics and Dentofacial Orthopaedics, Maharana Pratap Dental College, Kanpur, Uttar Pradesh, India.

出版信息

J Int Oral Health. 2013 Oct;5(5):53-8. Epub 2013 Oct 26.

PMID:24324305
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3845285/
Abstract

BACKGROUND

This study aimed to assess the dental and periodontal health status of beta thalassemia major and sickle cell anemic patients in Bilaspur, Chattishgarh, India.

MATERIALS & METHODS: A total of 750 patients were included in the study. The patients were randomly divided into three groups I (n=250), II (n=250) and III (n=250), ranging from 3-15 years. After performing a thourough general examination, including their demographic data, intraoral examination was done using Decayed-Missing-Filled Teeth Index (DMFT Index), Plaque index (PI) and Gingival index (GI). Statistical analysis was done using statistical software SPSS 17.5 version. Chi square test & student t test was used for the comparison of study and control groups. The level of significance was set at P<0.05.

RESULTS

In the present study, it was found that, prevalence of dental caries and periodontal diseases was significantly more in beta thalassemic patients followed by sickle cell anemic patients than control group. However, when group I (beta thalassemia) was compared with group II (sickle cell anemia), results were found to highly significant (P<0.001) only for decayed missing filled tooth.

CONCLUSION

Appropriate dental and periodontal care improves a patient's quality of life. Preventive dental care is must for thalassemic and Sickle cell disease patients. How to cite this article: Singh J, Singh N, Kumar A, Kedia NB, Agarwal A. Dental and Periodontal Health Status of Beta Thalassemia Major and Sickle Cell Anemic Patients: A Comparative Study. J Int Oral Health 2013; 5(5):53-8.

摘要

背景

本研究旨在评估印度恰蒂斯加尔邦比拉斯布尔市重型β地中海贫血和镰状细胞贫血患者的牙齿和牙周健康状况。

材料与方法

本研究共纳入750例患者。患者被随机分为三组,第一组(n = 250)、第二组(n = 250)和第三组(n = 250),年龄在3至15岁之间。在进行全面的全身检查,包括人口统计学数据后,使用龋失补牙指数(DMFT指数)、菌斑指数(PI)和牙龈指数(GI)进行口腔检查。使用统计软件SPSS 17.5版本进行统计分析。采用卡方检验和学生t检验对研究组和对照组进行比较。显著性水平设定为P<0.05。

结果

在本研究中发现,重型β地中海贫血患者的龋齿和牙周疾病患病率明显高于镰状细胞贫血患者,且二者均高于对照组。然而,当将第一组(重型β地中海贫血)与第二组(镰状细胞贫血)进行比较时,仅龋失补牙结果显示差异极显著(P<0.001)。

结论

适当的牙齿和牙周护理可改善患者的生活质量。对于地中海贫血和镰状细胞病患者,预防性牙齿护理必不可少。如何引用本文:Singh J, Singh N, Kumar A, Kedia NB, Agarwal A. 重型β地中海贫血和镰状细胞贫血患者的牙齿和牙周健康状况:一项比较研究。《国际口腔健康杂志》2013年;5(5):53 - 8。

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