El Mobadder Marwan, Nammour Samir, Matys Jacek, Grzech-Leśniak Kinga
Dental Surgery Department, Wroclaw Medical University, 50-425 Wroclaw, Poland.
Department of Dental Sciences, Faculty of Medicine, University of Liege, 4000 Liege, Belgium.
Life (Basel). 2022 Oct 19;12(10):1637. doi: 10.3390/life12101637.
Increasing the disinfection during non-surgical treatment of periodontitis is primordial. This study assesses the effectiveness of sodium hypochlorite and a 980 nm diode laser in non-surgical treatment of periodontitis. Thirty sites of localized periodontitis with a probing pocket depth (PPD) of ≥ 6 mm were included. Fifteen underwent scaling root planing (SRP group) and 15 underwent SRP + 0.5% NaOCl and a 980 nm diode laser (study group). A biological molecular test and real time polymerase chain reaction (RT-PCR) were performed before (T0) and after intervention (T1). Total bacterial count and counts of Porphyromonas gingivalis, Treponema denticola, Tannerella forsythia, Prevotella intermedia, Peptostreptococcus micros, Fusobacterium nucleatum, Aggregatibacter actinomycetemcomitans, Eubacterium nodatum, Capnocytophaga gingivalis were assessed. Plaque index (PI), bleeding on probing (BOP), gingival recession (GR), PPD and clinical attachment loss (CAL) were evaluated at T0, and 3 and 6 months after. Study group showed a statistically significant reduction of TBC (5.66 × 10 CFU/mL) compared to SRP (6.2 × 10 CFU/mL). Both groups showed a statistically significant reduction of Treponema denticola, Tannerella forsythia, Prevotella intermedia, Peptostrep. (micromonas) micros and Fusobacterium nucleatum; however, a significant reduction of Eubacterium nodatum and Capnocytophaga gingivalis was observed in the study group. At T6, both groups had a statistically significant reduction of PI, BOP, GR, PD and CAL. The study group showed more GR compared to SRP and a significant reduction of PD (4.03 mm ± 0.49) compared to SRP (5.28 mm ± 0.67). This study reveals that NaOCl and a diode laser are effective as an adjunctive to the non-surgical treatment of periodontitis.
在牙周炎的非手术治疗过程中加强消毒至关重要。本研究评估次氯酸钠和980纳米二极管激光在牙周炎非手术治疗中的有效性。纳入了30个探诊袋深度（PPD）≥6毫米的局限性牙周炎部位。15个部位接受了龈下刮治术和根面平整术（SRP组），15个部位接受了SRP + 0.5%次氯酸钠和980纳米二极管激光治疗（研究组）。在干预前（T0）和干预后（T1）进行了生物分子检测和实时聚合酶链反应（RT-PCR）。评估了总细菌计数以及牙龈卟啉单胞菌、具核梭杆菌、福赛坦纳菌、中间普氏菌、微小消化链球菌、具核梭杆菌、伴放线聚集杆菌、诺氏真杆菌、牙龈二氧化碳嗜纤维菌的计数。在T0以及3个月和6个月后评估菌斑指数（PI）、探诊出血（BOP）、牙龈退缩（GR）、PPD和临床附着丧失（CAL）。研究组显示总细菌计数（5.66×10 CFU/mL）相比于SRP组（6.2×10 CFU/mL）有统计学意义的降低。两组均显示具核梭杆菌、福赛坦纳菌、中间普氏菌、微小消化链球菌和具核梭杆菌有统计学意义的减少；然而，研究组中诺氏真杆菌和牙龈二氧化碳嗜纤维菌有显著减少。在T6时，两组的PI、BOP、GR、PD和CAL均有统计学意义的降低。研究组相比于SRP组显示出更多的牙龈退缩，并且与SRP组（5.28毫米±0.67）相比，PD有显著降低（4.03毫米±0.49）。本研究表明，次氯酸钠和二极管激光作为牙周炎非手术治疗的辅助手段是有效的。
