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苯氧基吡啶作为农药活性骨架的进展。

Advancement of Phenoxypyridine as an Active Scaffold for Pesticides.

机构信息

College of Science, China Agricultural University, Beijing 100193, China.

Department of Laboratory Animal Science, Peking University Health Science Center, Beijing 100191, China.

出版信息

Molecules. 2022 Oct 11;27(20):6803. doi: 10.3390/molecules27206803.

Abstract

Phenoxypyridine, the bioisostere of diaryl ethers, has been widely introduced into bioactive molecules as an active scaffold, which has different properties from diaryl ethers. In this paper, the bioactivities, structure-activity relationships, and mechanism of compounds containing phenoxypyridine were summarized, which may help to explore the lead compounds and discover novel pesticides with potential bioactivities.

摘要

苯并氧嘧啶,二芳基醚的生物等排体,已被广泛引入生物活性分子作为活性支架,其性质与二芳基醚不同。本文综述了含苯并氧嘧啶化合物的生物活性、构效关系和作用机制,这可能有助于探索先导化合物,发现具有潜在生物活性的新型农药。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1bad/9610772/5c481d0125d2/molecules-27-06803-g001.jpg

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