College of Science, China Agricultural University, Beijing 100193, China.
Department of Laboratory Animal Science, Peking University Health Science Center, Beijing 100191, China.
Molecules. 2022 Oct 11;27(20):6803. doi: 10.3390/molecules27206803.
Phenoxypyridine, the bioisostere of diaryl ethers, has been widely introduced into bioactive molecules as an active scaffold, which has different properties from diaryl ethers. In this paper, the bioactivities, structure-activity relationships, and mechanism of compounds containing phenoxypyridine were summarized, which may help to explore the lead compounds and discover novel pesticides with potential bioactivities.
苯并氧嘧啶,二芳基醚的生物等排体,已被广泛引入生物活性分子作为活性支架,其性质与二芳基醚不同。本文综述了含苯并氧嘧啶化合物的生物活性、构效关系和作用机制,这可能有助于探索先导化合物,发现具有潜在生物活性的新型农药。