Yi Zixi, Yao Zhongqiang, Xu Dan, Xu Chuanhui, Fang Wenqiang, Guo Zhanfei, Wang Yong, Huang Jianlin, Li Qin, Zhang Hong, Huang Anbin, Wu Lijun, Wu Zhenbiao, Guo Huifang, Zhang Fengxiao, Lu Jing, Zhang Zhenchun, Yu Zhongming, Da Zhanyun, Luo Li, Wu Bin, Wu Henglian, Zeng Lin, Mu Rong
Department of Rheumatology and Immunology, Peking University Third Hospital, Beijing 100191, China.
Department of Rheumatology, Allergy and Immunology, Tan Tock Seng Hospital, Singapore 999002, Singapore.
Vaccines (Basel). 2022 Sep 23;10(10):1604. doi: 10.3390/vaccines10101604.
The coronavirus disease 2019 (COVID-19) pandemic has imposed enormous morbidity and mortality burdens. Patients with rheumatic diseases (RDs) are vulnerable to the COVID-19 infection, given their immunocompromised status. Ensuring acceptance of the COVID-19 vaccine is important and has attracted attention by health professionals. In this study, we designed an online cross-sectional survey that used an online questionnaire from 8 May 2021 to 4 October 2021. Attitudes toward the COVID-19 vaccination, personal information, current disease activity status, adverse events (AEs), and knowledge sources of vaccines were collected. Descriptive statistics, nonparametric tests, and ordinal logistic regression were used to analyze the data. A total of 1022 questionnaires were received, among which 70.2% (720/1022) of patients with RDs agreed to vaccination, while only 31.6% of patients were actually vaccinated. Male, employed, high-income patients and those with inactive disease showed a more positive attitude. Concerns of AEs and disease flare were the main factors affecting vaccination willingness. Only 29.6% (304/1022) of patients thought they had received enough information about the COVID-19 vaccine from their doctors. In conclusion, most patients with RDs in China intended to get vaccinated, although the vaccination rate in this particular population was low. Rheumatologists should take more responsibility in COVID-19 vaccination education of patients with RDs.
2019年冠状病毒病（COVID-19）大流行带来了巨大的发病和死亡负担。风湿性疾病（RD）患者由于免疫功能低下，易感染COVID-19。确保COVID-19疫苗的接种很重要，并且已引起卫生专业人员的关注。在本研究中，我们设计了一项在线横断面调查，使用在线问卷，时间从2021年5月8日至2021年10月4日。收集了对COVID-19疫苗接种的态度、个人信息、当前疾病活动状态、不良事件（AE）以及疫苗知识来源。使用描述性统计、非参数检验和有序逻辑回归分析数据。共收到1022份问卷，其中70.2%（720/1022）的RD患者同意接种疫苗，而实际接种的患者仅占31.6%。男性、就业、高收入患者以及疾病不活动的患者态度更为积极。对不良事件和疾病复发的担忧是影响接种意愿的主要因素。只有29.6%（304/1022）的患者认为他们从医生那里获得了足够的关于COVID-19疫苗的信息。总之，中国大多数RD患者打算接种疫苗，尽管这一特定人群的接种率较低。风湿病学家应在RD患者的COVID-19疫苗接种教育中承担更多责任。
