Tian Dandan, Nie Wenjian, Sun Yanhong, Ye Qing
Department of Clinical Laboratory, The Children's Hospital, Zhejiang University School of Medicine, National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou 310052, China.
Vaccines (Basel). 2022 Oct 11;10(10):1699. doi: 10.3390/vaccines10101699.
From December 2021 to May 2022, the Omicron BA.1 and BA.2 subvariants successively became the most dominant strains in many countries around the world. Subsequently, Omicron subvariants have emerged, and Omicron has been classified into five main lineages, including BA.1, BA.2, BA.3, BA.4, BA.5, and some sublineages (BA.1.1, BA.2.12.1, BA.2.11, BA.2.75, BA.4.6, BA.5.1, and BA.5.2). The recent emergence of several Omicron subvariants has generated new concerns about further escape from immunity induced by prior infection and vaccination and the creation of new COVID-19 waves globally. In particular, BA.5 (first found in southern Africa, February 2022) displays a higher transmissibility than other Omicron subvariants and is replacing the previously circulating BA.1 and BA.2 in several countries.
2021年12月至2022年5月期间，奥密克戎BA.1和BA.2亚变体先后成为全球许多国家最主要的毒株。随后，奥密克戎亚变体不断出现，奥密克戎已被分为五个主要谱系，包括BA.1、BA.2、BA.3、BA.4、BA.5，以及一些亚谱系（BA.1.1、BA.2.12.1、BA.2.11、BA.2.75、BA.4.6、BA.5.1和BA.5.2）。近期出现的几种奥密克戎亚变体引发了新的担忧，即它们可能会进一步逃避先前感染和疫苗接种所诱导的免疫力，并在全球引发新一波新冠疫情。特别是BA.5（2022年2月首次在南非发现）的传播性高于其他奥密克戎亚变体，正在一些国家取代此前流行的BA.1和BA.2。
