Kang Weixi, Hernández Sònia Pineda, Rahman Md Shahinoor, Voigt Katharina, Malvaso Antonio
Computational, Cognitive and Clinical Neuroimaging Laboratory, Division of Brain Sciences, Department of Medicine, Imperial College London, London, United Kingdom.
Euncet Business School, Polytechnic University of Catalonia, Barcelona, Spain.
Front Psychol. 2022 Oct 10;13:651547. doi: 10.3389/fpsyg.2022.651547. eCollection 2022.
As one of the core executive functions, inhibition plays an important role in human life through development. Inhibitory control is defined as the ability to suppress actions when they are unlikely to accomplish valuable results. Contemporary neuroscience has investigated the underlying neural mechanisms of inhibitory control. The controversy started to arise, which resulted in two schools of thought: a modulatory and a network account of inhibitory control. In this systematic review, we survey developmental mechanisms in inhibitory control as well as neurodevelopmental diseases related to inhibitory dysfunctions. This evidence stands against the modulatory perspective of inhibitory control: the development of inhibitory control does not depend on a dedicated region such as the right inferior frontal gyrus (rIFG) but relies on a more broadly distributed network.
作为核心执行功能之一，抑制在人类生命发展过程中起着重要作用。抑制控制被定义为在行动不太可能产生有价值结果时抑制行动的能力。当代神经科学已经研究了抑制控制的潜在神经机制。争议由此产生，形成了两种观点：抑制控制的调节性观点和网络观点。在本系统综述中，我们考察了抑制控制的发展机制以及与抑制功能障碍相关的神经发育疾病。这一证据与抑制控制的调节性观点相悖：抑制控制的发展并不依赖于诸如右下额叶回（rIFG）这样的特定区域，而是依赖于分布更广的网络。
