声刺激强度对儿童气导前庭诱发肌源性电位的影响。
Effects of acoustic stimulation intensity on air-conducted vestibular evoked myogenic potential in children.
作者信息
Xiao Qianwen, Zhang Qin, Wu Qiong, Shen Jiali, Wang Lu, Chen Yanfei, Lv Jingrong, Yang Jun, Jin Yulian, Zhang Qing
机构信息
Department of Otorhinolaryngology-Head and Neck Surgery, Xinhua Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, China.
Shanghai Jiaotong University School of Medicine Ear Institute, Shanghai, China.
出版信息
Front Neurol. 2022 Oct 11;13:996246. doi: 10.3389/fneur.2022.996246. eCollection 2022.
OBJECTIVE
To investigate the effects of acoustic stimulation intensity on ocular and cervical vestibular evoked myogenic potential (oVEMP and cVEMP) responses elicited by air-conducted sound (ACS) in healthy children.
METHODS
Thirteen healthy children aged 4-10 years and 20 healthy adults aged 20-40 years with normal hearing and tympanometry were enrolled in this study. All subjects received oVEMP and cVEMP tests under different acoustic stimulation intensities (131, 126, 121, 116, 111 and 106 dB SPL). Mean n1 latency, p1 latency, interpeak latency, amplitude and response rate were investigated and analyzed.
RESULTS
As the acoustic stimulation intensity decreased, for oVEMP, the response rate of children decreased from 100% (131, 126 and 121 dB SPL) to 57.69% (116 dB SPL), 26.92% (111 dB SPL) and 11.54% (106 dB SPL). The response rate of adults decreased from 100% (131 and 126 dB SPL) to 95% (121 dB SPL), 55% (116 dB SPL), 12.5% (111 dB SPL) and 2.5% (106 dB SPL). There were lower n1 latency, p1 latency and higher amplitude in children when comparing by acoustic stimulation intensities ( < 0.05). Regarding cVEMP, the response rate of children decreased from 100% (131, 126 and 121 dB SPL) to 88.46% (116 dB SPL), 53.85% (111 dB SPL) and 26.92% (106 dB SPL). The response rate of adults decreased from 100% (131 and 126 dB SPL) to 95% (121 dB SPL), 85% (116 dB SPL), 37.5% (111 dB SPL) and 7.5% (106 dB SPL). A statistically significant difference was found in amplitude at different acoustic stimulation intensities in both children and adults ( < 0.05). When stimulated by 131 dB SPL acoustic stimulation, there were lower n1 latency, p1 latency and higher amplitude in children in oVEMP and cVEMP compared with adults ( < 0.05).
CONCLUSION
The response rate and amplitude of oVEMP and cVEMP in children and adults presented significant differences with a decrease in acoustic stimulation intensity. In this study, using 121 dB SPL for children and 126 dB SPL for adults during VEMP test could be regarded as safer stimulation intensities and thus reduced sound exposure.
目的
探讨声刺激强度对健康儿童气导声音（ACS）诱发的眼和颈前庭诱发肌源性电位（oVEMP和cVEMP）反应的影响。
方法
本研究纳入了13名4 - 10岁听力和鼓室图正常的健康儿童以及20名20 - 40岁听力和鼓室图正常的健康成年人。所有受试者在不同声刺激强度（131、126、121、116、111和106 dB SPL）下接受oVEMP和cVEMP测试。研究并分析平均n1潜伏期、p1潜伏期、峰间潜伏期、波幅和反应率。
结果
随着声刺激强度降低，对于oVEMP，儿童的反应率从100%（131、126和121 dB SPL）降至57.69%（116 dB SPL）、26.92%（111 dB SPL）和11.54%（106 dB SPL）。成年人的反应率从100%（131和126 dB SPL）降至95%（121 dB SPL）、55%（116 dB SPL）、12.5%（111 dB SPL）和2.5%（106 dB SPL）。按声刺激强度比较，儿童的n1潜伏期、p1潜伏期较低，波幅较高（P<0.05）。对于cVEMP，儿童的反应率从100%（131、126和121 dB SPL）降至88.46%（116 dB SPL）、53.85%（111 dB SPL）和26.92%（106 dB SPL）。成年人的反应率从100%（131和126 dB SPL）降至95%（121 dB SPL）、85%（116 dB SPL）、37.5%（111 dB SPL）和7.5%（106 dB SPL）。儿童和成年人在不同声刺激强度下的波幅均存在统计学显著差异（P<0.05）。当受到131 dB SPL声刺激时 , oVEMP和cVEMP中儿童的n1潜伏期、p1潜伏期低于成年人，波幅高于成年人（P<0.05）。
结论
儿童和成年人oVEMP和cVEMP的反应率和波幅随声刺激强度降低呈现显著差异。在本研究中，VEMP测试期间儿童使用121 dB SPL、成年人使用126 dB SPL可视为更安全的刺激强度，从而减少声音暴露。
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