ENT Clinic, Medicana International Hospital, Ankara, Turkey.
Faculty of Medicine, Department of ENT, Atilim University, Ankara, Turkey.
Eur Arch Otorhinolaryngol. 2022 May;279(5):2339-2343. doi: 10.1007/s00405-021-06936-w. Epub 2021 Jun 15.
To compare the effectiveness of chirp and tone burst stimuli in oVEMP and cVEMP testing for healthy adults METHODS: This study was conducted in 56 healthy volunteers (112 ears). Ocular and cervical VEMP (oVEMP, cVEMP) tests were performed for each participant using tone burst and chirp stimuli. VEMP response rates, latency of each peak (p1-n1, n1-p1), peak to peak amplitude (p1-n1 amplitude and n1-p1 amplitude), and rectified amplitudes were measured and compared between these two different stimuli.
VEMP response rates with chirp stimuli are higher than the tone burst stimuli for both cVEMP and oVEMP tests (The difference was statistically significant for oVEMP, p = 0.001). Chirp stimuli have higher p1n1 amplitude and rectified amplitude and shorter p1and n1 latency then tone burst stimuli for cVEMP (p = 0.015, p = 0.007, p < 0.001, p < 0.001, respectively). Chirp stimuli also have higher n1p1 amplitude and shorter n1and p1 latency then tone burst stimuli for oVEMP (p = 0.006, p < 0.001, p < 0.001, respectively).
The present findings show that the chirp stimulus triggers earlier VEMP responses with higher amplitudes than the tone burst stimulus during cVEMP and oVEMP testing. VEMP response rate with chirp stimulus is also higher than the tone burst. Therefore chirp stimulus can be used in VEMP testing as effectively as, if not more than, tone burst stimulus in clinical practice.
比较啁啾和短音爆裂刺激在健康成年人眼震电图（oVEMP）和颈肌前庭诱发肌源性电位（cVEMP）测试中的效果。
本研究纳入了 56 名健康志愿者（112 耳）。对每位参与者使用短音爆裂和啁啾刺激进行了眼震电图和颈肌前庭诱发肌源性电位（oVEMP，cVEMP）测试。测量并比较了两种不同刺激下的 VEMP 反应率、各峰值（p1-n1、n1-p1）潜伏期、峰间振幅（p1-n1 振幅和 n1-p1 振幅）和整流振幅。
与短音爆裂刺激相比，啁啾刺激在 cVEMP 和 oVEMP 测试中均具有更高的 VEMP 反应率（oVEMP 测试中差异具有统计学意义，p=0.001）。与短音爆裂刺激相比，啁啾刺激在 cVEMP 中具有更高的 p1n1 振幅和整流振幅以及更短的 p1 和 n1 潜伏期（p=0.015、p=0.007、p<0.001、p<0.001）。啁啾刺激在 oVEMP 中也具有更高的 n1p1 振幅和更短的 n1 和 p1 潜伏期（p=0.006、p<0.001、p<0.001）。
本研究结果表明，在 cVEMP 和 oVEMP 测试中，啁啾刺激比短音爆裂刺激更早引发 VEMP 反应，且具有更高的振幅。啁啾刺激的 VEMP 反应率也高于短音爆裂刺激。因此，啁啾刺激可在 VEMP 测试中有效应用，其效果与短音爆裂刺激相当，甚至可能更优。
