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The Lymphatic System in Neurological Disease and Alzheimer's Disease. A Brief Editorial.

作者信息

Pappolla Miguel A, Carare Roxana O, Poeggeler Burkhand, Wisniewski Thomas, Sambamurti Kumar

机构信息

Department of Neurology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA.

Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ, UK.

出版信息

Curr Alzheimer Res. 2022;19(10):689-693. doi: 10.2174/1567205020666221028111517.

DOI:10.2174/1567205020666221028111517
PMID:36306458
Abstract
摘要

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Curr Neuropharmacol. 2023;21(2):380-391. doi: 10.2174/1570159X20666220411091332.
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Brain Fluid Channels for Metabolite Removal.脑内液流通道与代谢产物清除。
Physiol Res. 2022 Apr 30;71(2):199-208. doi: 10.33549/physiolres.934802. Epub 2022 Mar 28.
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Innate immunity stimulation via CpG oligodeoxynucleotides ameliorates Alzheimer's disease pathology in aged squirrel monkeys.
通过 CpG 寡脱氧核苷酸刺激先天免疫可改善老年松鼠猴的阿尔茨海默病病理。
Brain. 2021 Aug 17;144(7):2146-2165. doi: 10.1093/brain/awab129.
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Amyloid-beta is present in human lymph nodes and greatly enriched in those of the cervical region.β-淀粉样蛋白存在于人类淋巴结中,且在颈部淋巴结中大量富集。
Alzheimers Dement. 2022 Feb;18(2):205-210. doi: 10.1002/alz.12385. Epub 2021 May 31.
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Vascular α1A Adrenergic Receptors as a Potential Therapeutic Target for IPAD in Alzheimer's Disease.血管α1A肾上腺素能受体作为阿尔茨海默病中IPAD的潜在治疗靶点
Pharmaceuticals (Basel). 2020 Sep 22;13(9):261. doi: 10.3390/ph13090261.
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Meningeal Lymphatics: A Review and Future Directions From a Clinical Perspective.脑膜淋巴管:从临床角度的综述与未来方向
Neurosci Insights. 2019 Dec 31;14:1179069519889027. doi: 10.1177/1179069519889027. eCollection 2019.
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Functional aspects of meningeal lymphatics in ageing and Alzheimer's disease.脑膜淋巴管在衰老和阿尔茨海默病中的功能方面。
Nature. 2018 Aug;560(7717):185-191. doi: 10.1038/s41586-018-0368-8. Epub 2018 Jul 25.
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Melatonin Treatment Enhances Aβ Lymphatic Clearance in a Transgenic Mouse Model of Amyloidosis.褪黑素治疗增强淀粉样变性转基因小鼠模型中β淀粉样蛋白的淋巴清除率。
Curr Alzheimer Res. 2018;15(7):637-642. doi: 10.2174/1567205015666180411092551.
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Semin Plast Surg. 2018 Feb;32(1):5-11. doi: 10.1055/s-0038-1635118. Epub 2018 Apr 9.
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Nat Commun. 2017 Nov 10;8(1):1434. doi: 10.1038/s41467-017-01484-6.