儿童期睡眠障碍与成年期吸烟轨迹的关联：纵向 TEMPO 队列研究。

Association between Sleep Disturbances During Childhood and Smoking Trajectories During Adulthood: The Longitudinal TEMPO Cohort Study.

机构信息

INSERM, Institut Pierre Louis d'Épidémiologie et de Santé Publique (IPLESP), Equipe de Recherche en Epidémiologie Sociale (ERES), Sorbonne Université, Paris, France.

Unité de Recherche « Biostatistique, Traitement et Modélisation des données biologiques » BioSTM - UR 7537, Université Paris Cité, Paris, France.

出版信息

Behav Sleep Med. 2023 Sep 3;21(5):556-569. doi: 10.1080/15402002.2022.2137511. Epub 2022 Oct 29.

DOI:10.1080/15402002.2022.2137511

PMID:36308769

Abstract

OBJECTIVE

This study examined the longitudinal association between child sleep disturbances from ages 3 to 16 and smoking in adulthood among subjects from a French cohort study.

METHODS

Data from 2,134 subjects who participated in the French TEMPO cohort from 1991 to 2018 were used. Sleep disturbances observed from ages 3 to 16 years defined our exposure. Tobacco consumption trajectories constitute our outcomes and were ascertained by using Group-Based Trajectory Modeling, a semiparametric probabilistic method that hypothesizes the existence of distinct developmental trajectories over time within one population. The impact of SDs in childhood on adulthood's Tobacco consumption were studied using multinomial logistic regression.

RESULTS

Sleep disturbances at 16 years or under were observed in 26.5% of participants. Five smoking trajectories were defined: "non-smokers", "decrease in consumption at age 20 years", "low-level tobacco use", "smoking followed by cessation at age 30 years" and "high-level tobacco use". No statistically significant association between sleep disturbances and smoking trajectories was found. Compared with nonsmokers, adjusted odds-ratios and 95% Confidence Intervals for each trajectory were respectively: 0.81 [0.52-1.26], 1.28 [0.74-2.22], 1.37 [0.88-2.15] and 1.01 [0.60-1.69].

CONCLUSION

These results suggest that smoking in adulthood may not be related to sleep disturbances in childhood.

摘要

目的

本研究考察了从 3 岁到 16 岁儿童睡眠障碍与成年吸烟之间的纵向关联，研究对象来自法国队列研究。

方法

使用了 2134 名参加 1991 年至 2018 年法国 TEMPO 队列研究的受试者的数据。从 3 岁到 16 岁观察到的睡眠障碍定义了我们的暴露。吸烟轨迹构成了我们的结果，并通过基于群组的轨迹建模来确定，这是一种半参数概率方法，假设在一个人群中随着时间的推移存在不同的发展轨迹。使用多项逻辑回归研究了儿童时期的 SD 对成年期烟草消费的影响。

结果

26.5%的参与者存在 16 岁或以下的睡眠障碍。定义了五条吸烟轨迹：“不吸烟者”、“20 岁时消费减少”、“低水平烟草使用”、“30 岁时吸烟后停止”和“高水平烟草使用”。睡眠障碍与吸烟轨迹之间没有统计学上的显著关联。与不吸烟者相比，每种轨迹的调整后优势比和 95%置信区间分别为：0.81 [0.52-1.26]、1.28 [0.74-2.22]、1.37 [0.88-2.15]和 1.01 [0.60-1.69]。