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高血压患者在 COVID-19 大流行期间血压变化结果:美国三个医疗机构的时间序列分析。

Changes in Blood Pressure Outcomes Among Hypertensive Individuals During the COVID-19 Pandemic: A Time Series Analysis in Three US Healthcare Organizations.

机构信息

Division of General Internal Medicine, Cedars-Sinai Medical Center, Los Angeles, CA (H.G., T.K.N.).

Division of General Internal Medicine, Department of Medicine, Columbia University Irving Medical Center, New York, NY (N.L.-D., A.E.M., Y.Z.).

出版信息

Hypertension. 2022 Dec;79(12):2733-2742. doi: 10.1161/HYPERTENSIONAHA.122.19861. Epub 2022 Nov 1.

Abstract

BACKGROUND

The COVID-19 pandemic may have negatively affected medical care for and self-management of chronic hypertension. We sought to examine the impact of the pandemic on blood pressure (BP) among individuals with hypertension.

METHODS

Using an interrupted time series analysis, we compared the level and trend (slope) of BP outcomes before the public health emergency declaration (prepandemic period: August 2018 through January 2020) versus after the stay-at-home orders (pandemic period: April 2020 through November 2020) among adults with hypertension followed at 3 large health systems (n=137 593). Outcomes include systolic and diastolic BP recorded in electronic health records and the proportion of individuals with BP <140/90 mm Hg.

RESULTS

The number of BP measurements substantially dropped early in the pandemic and then gradually increased. During the pandemic period, systolic and diastolic BP increased by 1.79 mm Hg (95% CI, 1.57-2.01; <0.001) and 1.30 mm Hg (95% CI, 1.18-1.42; <0.001), respectively, compared with the prepandemic period. Similarly, the proportion of patients with controlled BP decreased by 3.43 percentage points (95% CI, -3.97 to -2.90; <0.001). A trend showing increasing control in the prepandemic period (+3.19 percentage points per year [95% CI, +2.96 to +3.42]; <0.001) flattened during the pandemic period (+0.27 percentage points per year [95% CI, -0.81 to -1.37]; =0.62).

CONCLUSIONS

The first 8 months of the pandemic were associated with worsening BP outcomes among individuals with hypertension. Opportunities to ensure ongoing access to health care with telemedicine and home BP monitoring may mitigate adverse impacts on BP control for future disasters/emergencies.

摘要

背景

COVID-19 大流行可能对慢性高血压的医疗保健和自我管理产生负面影响。我们旨在研究大流行对高血压患者血压的影响。

方法

我们使用中断时间序列分析,比较了在公共卫生紧急情况宣布前(大流行前:2018 年 8 月至 2020 年 1 月)与在家工作令后(大流行期间:2020 年 4 月至 2020 年 11 月)期间,在 3 家大型医疗保健系统接受治疗的高血压成年人的血压(BP)结果的水平和趋势(斜率)(n=137593)。结果包括电子健康记录中记录的收缩压和舒张压以及血压<140/90mmHg 的个体比例。

结果

大流行早期血压测量数量大幅下降,然后逐渐增加。在大流行期间,与大流行前相比,收缩压和舒张压分别增加了 1.79mmHg(95%置信区间,1.57-2.01;<0.001)和 1.30mmHg(95%置信区间,1.18-1.42;<0.001)。同样,血压控制良好的患者比例下降了 3.43 个百分点(95%置信区间,-3.97 至-2.90;<0.001)。大流行前血压控制呈逐渐改善的趋势(每年增加 3.19 个百分点[95%置信区间,2.96 至 3.42];<0.001),在大流行期间趋于平稳(每年增加 0.27 个百分点[95%置信区间,-0.81 至-1.37];=0.62)。

结论

大流行的头 8 个月与高血压患者的血压结果恶化有关。通过远程医疗和家庭血压监测确保获得持续医疗保健的机会,可能会减轻未来灾难/紧急情况对血压控制的不利影响。

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