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血压控制在 COVID-19 大流行期间中断:PCORnet 血压控制实验室。

Disruption in Blood Pressure Control With the COVID-19 Pandemic: The PCORnet Blood Pressure Control Laboratory.

机构信息

Department of Quantitative Health Sciences, Mayo Clinic, Rochester, MN; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.

Department of Pharmacotherapy and Translational Research, College of Pharmacy, University of Florida, Gainesville; Division of Cardiovascular Medicine, College of Medicine, University of Florida, Gainesville.

出版信息

Mayo Clin Proc. 2023 May;98(5):662-675. doi: 10.1016/j.mayocp.2022.12.024. Epub 2023 Jan 25.

Abstract

OBJECTIVE

To explore trends in blood pressure (BP) control before and during the COVID-19 pandemic.

PATIENTS AND METHODS

Health systems participating in the National Patient-Centered Clinical Research Network (PCORnet) Blood Pressure Control Laboratory Surveillance System responded to data queries, producing 9 BP control metrics. Averages of the BP control metrics (weighted by numbers of observations in each health system) were calculated and compared between two 1-year measurement periods (January 1, 2019, through December 31, 2019, and January 1, 2020, through December 31, 2020).

RESULTS

Among 1,770,547 hypertensive persons in 2019, BP control to <140/<90 mm Hg varied across 24 health systems (range, 46%-74%). Reduced BP control occurred in most health systems with onset of the COVID-19 pandemic; the weighted average BP control was 60.5% in 2019 and 53.3% in 2020. Reductions were also evident for BP control to <130/<80 mm Hg (29.9% in 2019 and 25.4% in 2020) and improvement in BP (reduction of 10 mm Hg in systolic BP or achievement of systolic BP <140 mm Hg; 29.7% in 2019 and 23.8% in 2020). Two BP control process metrics exhibited pandemic-associated disruption: repeat visit in 4 weeks after a visit with uncontrolled hypertension (36.7% in 2019 and 31.7% in 2020) and prescription of fixed-dose combination medications among those with 2 or more drug classes (24.6% in 2019 and 21.5% in 2020).

CONCLUSION

BP control decreased substantially during the COVID-19 pandemic, with a corresponding reduction in follow-up health care visits among persons with uncontrolled hypertension. It is unclear whether the observed decline in BP control during the pandemic will contribute to future cardiovascular events.

摘要

目的

探索 COVID-19 大流行前后血压(BP)控制的趋势。

患者和方法

参与国家以患者为中心的临床研究网络(PCORnet)BP 控制实验室监测系统的医疗系统对数据查询做出了回应,生成了 9 项 BP 控制指标。对每个医疗系统中观察数量加权的 BP 控制指标平均值进行了计算,并在两个为期 1 年的测量期(2019 年 1 月 1 日至 12 月 31 日和 2020 年 1 月 1 日至 12 月 31 日)之间进行了比较。

结果

在 2019 年的 1770547 名高血压患者中,24 个医疗系统之间的<140/<90mmHg 血压控制情况各不相同(范围为 46%-74%)。随着 COVID-19 大流行的开始,大多数医疗系统的血压控制情况恶化;2019 年加权平均血压控制率为 60.5%,2020 年为 53.3%。对于<130/<80mmHg 的血压控制情况(2019 年为 29.9%,2020 年为 25.4%)和血压改善(收缩压降低 10mmHg 或收缩压<140mmHg;2019 年为 29.7%,2020 年为 23.8%)也同样明显。两项 BP 控制过程指标显示出与大流行相关的中断:高血压控制不佳的就诊后 4 周内的重复就诊(2019 年为 36.7%,2020 年为 31.7%)以及服用两种或两种以上药物类别的固定剂量联合药物(2019 年为 24.6%,2020 年为 21.5%)。

结论

COVID-19 大流行期间,BP 控制显著下降,高血压控制不佳患者的后续医疗保健就诊次数相应减少。尚不清楚大流行期间观察到的 BP 控制下降是否会导致未来的心血管事件。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/df7d/9874044/7c968d1e5b78/gr1_lrg.jpg

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