da Silva Maria do S B, de Araujo Jhudson G L, Bento Júlia C C V, de Azevedo Amanda M, Souto Carlos R O, Dos Anjos Aécia S D, de Araújo Aruzza M M, da Silva Djalma R, Menezes Fabrício G, Gondim Amanda D, Cavalcanti Lívia N
Federal University of Rio Grande do Norte, Institute of Chemistry 59072-970 Natal RN Brazil
RSC Adv. 2022 Sep 29;12(43):27889-27894. doi: 10.1039/d2ra04057c. eCollection 2022 Sep 28.
An operationally simple and highly selective method for the decarboxylation of fatty acids under remarkably mild conditions is described herein. The activation of the aliphatic carboxylic acids by esterification with -hydroxyphthalimide (NHPI) enabled efficient deoxygenation to synthesize -alkanes in up to 67% yield, employing inexpensive PMHS as a hydrogen source, NiCl·6HO, bipyridine, and zinc in THF. In contrast to the conventional thermo-catalytic approaches, this protocol does not require high temperature and high pressure of hydrogen gas to deoxygenate biomass-derived carboxylic acids, thus representing an attractive alternative for producing drop-in biofuels.
本文描述了一种操作简单且选择性高的方法，可在非常温和的条件下使脂肪酸脱羧。通过用 - 羟基邻苯二甲酰亚胺（NHPI）酯化来活化脂肪族羧酸，以廉价的聚甲基氢硅氧烷（PMHS）作为氢源，在四氢呋喃中使用NiCl·6H₂O、联吡啶和锌，能够实现高效脱氧，以高达67%的产率合成 - 烷烃。与传统的热催化方法不同，该方案不需要高温高压氢气来使生物质衍生的羧酸脱氧，因此是生产可直接替代的生物燃料的一种有吸引力的替代方法。
