Enbanathan Saravanan, Munusamy Sathishkumar, Jothi Dhanapal, Manojkumar Selin, Manickam Saravanakumar, Iyer Sathiyanarayanan Kulathu
Department of Chemistry, School of Advanced Sciences and Vellore Institute of Technology Vellore-632014 India
Department of Chemistry, Faculty of Science, Chulalongkorn University Phayathai Rd., Pathumwan Bangkok 10330 Thailand
RSC Adv. 2022 Sep 29;12(43):27839-27845. doi: 10.1039/d2ra04874d. eCollection 2022 Sep 28.
A new photochromic fluorescence chemosensor was devised and effectively synthesized using benzothiazole and imidazopyridine derivatives. A "turn-on" fluorescence sensor BIPP for Zn detection was developed and has a quick response, excellent sensitivity, and remarkable selectivity over other metal ions. When Zn was added to the BIPP solution, a new strong fluorescence emission peak at 542 nm formed with a considerable increase in intensity. The fluorescence color of the BIPP solution changed from blue to bright green. The binding ratio 8 : 2 was found between BIPP and Zn by the results of Job's plot, HRMS and H-NMR. The detection limit (LOD) of BIPP towards Zn was determined to be 2.36 × 10, which is remarkably low. The ability to detect Zn in real water samples demonstrates that BIPP may also be used in environmental systems. Additionally, BIPP can be used to measure Zn levels in living cells.
利用苯并噻唑和咪唑并吡啶衍生物设计并有效合成了一种新型光致变色荧光化学传感器。开发了一种用于检测锌的“开启”型荧光传感器BIPP，它对锌具有快速响应、优异的灵敏度以及相对于其他金属离子的显著选择性。当向BIPP溶液中加入锌时，在542nm处形成了一个新的强荧光发射峰，强度显著增加。BIPP溶液的荧光颜色从蓝色变为亮绿色。通过Job曲线、高分辨质谱（HRMS）和氢核磁共振（H-NMR）结果发现BIPP与锌的结合比例为8∶2。BIPP对锌的检测限被确定为2.36×10，这一数值非常低。在实际水样中检测锌的能力表明BIPP也可用于环境系统。此外，BIPP可用于测量活细胞中的锌含量。
