Max Planck-Bristol Center for Minimal Biology, University of Bristol, 1 Tankard's Close, Bristol, BS8 1TD, UK.
Kennedy Institute of Rheumatology, University of Oxford, Roosevelt Drive, OX3 7FY, UK.
Nat Commun. 2022 Nov 2;13(1):6530. doi: 10.1038/s41467-022-33661-7.
Bottom-up synthetic biology provides new means to understand living matter by constructing minimal life-like systems. This principle can also be applied to study infectious diseases. Here we summarize approaches and ethical considerations for the bottom-up assembly of viral replication cycles.
自下而上的合成生物学为通过构建最小的类生命系统来理解生命物质提供了新的手段。这一原则也可以应用于传染病的研究。在这里,我们总结了自下而上组装病毒复制周期的方法和伦理考虑因素。