Fishman P S
Arch Neurol. 1987 Oct;44(10):1082-4. doi: 10.1001/archneur.1987.00520220078021.
Autopsy material from patients with posttraumatic paraplegia of long duration was examined to determine the extent of survival of corticospinal axons proximal to the injury. Spinal cord sections from sites above a functionally complete spinal cord injury were examined for the presence of axons, myelin, and gliosis. There was a marked depletion of axons from the corticospinal tract close to the region of injury. There appeared to be a gradual increase in the density of axons within the tract at increasing distance from the injury in all patients. Corticospinal axons appear to retract from the spinal cord injury site, but do not show progressive degeneration even years after a spinal cord injury.
对长期创伤性截瘫患者的尸检材料进行检查，以确定损伤近端皮质脊髓轴突的存活程度。对功能完全性脊髓损伤上方部位的脊髓切片进行检查，以确定轴突、髓鞘和神经胶质增生的情况。靠近损伤区域的皮质脊髓束轴突明显减少。在所有患者中，距损伤部位距离越远，该束内轴突密度似乎逐渐增加。皮质脊髓轴突似乎从脊髓损伤部位退缩，但即使在脊髓损伤多年后也未显示进行性变性。
