Malek Mahdavi Aida, Javadivala Zeinab, Khalili Yeganeh, Khalili Majid
Connective Tissue Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Tuberculosis and Lung Disease Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
Inflammopharmacology. 2023 Feb;31(1):241-251. doi: 10.1007/s10787-022-01091-y. Epub 2022 Nov 4.
The aim of the current systematic review was to gather the researches about the effect of quinoa (chenopodium quinoa) on inflammatory parameters interleukin-6 (IL-6), interleukin-1β (IL-1β), and tumor necrosis factor-alpha (TNF-α). Search was performed using PubMed, Scopus, WOS, ProQuest, and Google scholar databases without any restriction on language or publication date until July 2022 and search alert services were used to detect novel papers published after the initial search. Only 20 animal and in vitro investigations were eligible for this systematic review. According to in vitro researches and 8 of 14 animal investigations, IL-6, IL-1β, and TNF-α level decreased remarkably after quinoa administration, which indicates the capability of quinoa in alleviating inflammatory factors. Quinoa is favorable but not yet a confirmed agent for alleviating systemic inflammation in inflammatory diseases.
本系统评价的目的是收集有关藜麦（Chenopodium quinoa）对炎症参数白细胞介素-6（IL-6）、白细胞介素-1β（IL-1β）和肿瘤坏死因子-α（TNF-α）影响的研究。使用PubMed、Scopus、WOS、ProQuest和谷歌学术数据库进行检索，对语言或出版日期没有任何限制，截至2022年7月，并使用检索提醒服务来检测初始检索后发表的新论文。只有20项动物和体外研究符合本系统评价的要求。根据体外研究和14项动物研究中的8项，给予藜麦后IL-6、IL-1β和TNF-α水平显著降低，这表明藜麦具有减轻炎症因子的能力。藜麦是有益的，但尚未被确认为减轻炎症性疾病全身炎症的药物。
