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年龄对创伤患者死亡率的影响

Age as the Impact on Mortality Rate in Trauma Patients.

作者信息

Wongweerakit Onchuda, Akaraborworn Osaree, Sangthong Burapat, Thongkhao Komet

机构信息

Division of Trauma and Critical Care, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, Thailand.

出版信息

Crit Care Res Pract. 2022 Oct 26;2022:2860888. doi: 10.1155/2022/2860888. eCollection 2022.

Abstract

BACKGROUND

Globally, the fastest-growing population is that of older adults. Geriatric trauma patients pose a unique challenge to trauma teams because the aging process reduces their physiologic reserve. To date, no agreed-upon definition exists for the geriatric trauma patients, and the appropriate age cut point to consider patients at increased risk of mortality is unclear.

OBJECTIVES

To determine the age cut point at which age impacts the mortality rate in trauma patients in Thailand.

MATERIALS AND METHODS

This was a retrospective cohort and prognostic analysis study conducted in trauma patients ≥40 years. Patient data were retrieved from the trauma registry database and hospital information system in Songklanagarind Hospital. The estimated sample size of 1,509 patients was calculated based on the trauma registry data. The age with the maximum mortality rate was used as the cut point to define the elderly population. Hospital cost, intensive care unit (ICU) length of stay, gender, precomorbidity, mechanism of injury, injury severity score (ISS), and trauma and injury severity score were analyzed for any correlation with mortality, and whether or not they were associated with elderly trauma patients.

RESULTS

A total of 1,523 trauma patients ≥40 years were included in the study. The median age in both the survival and death groups was 61 years, with gender in both groups being similar ( value = 0.259). In the multivariate logistic regression analyses, the adjusted odds ratio (OR) showed that increasing age was significantly associated with mortality (OR = 1.05; 95% CI, 1.02-1.07; value <0.001). In the age group of 70 to 79 years and >80 years, the odds of mortality were significantly increased (OR 3.29, 95% CI, 1.24-8.68; value = 0.016 and OR 3.29, 95% CI, 1.27-12.24; value = 0.018, respectively).

CONCLUSION

Age is a significant risk factor for mortality in trauma patients. The mortality significantly increased at the age of 70 and higher.

摘要

背景

在全球范围内,增长最快的人群是老年人。老年创伤患者给创伤治疗团队带来了独特的挑战,因为衰老过程会降低他们的生理储备。迄今为止,对于老年创伤患者尚无公认的定义,且对于考虑死亡风险增加的患者的合适年龄切点尚不清楚。

目的

确定在泰国创伤患者中年龄影响死亡率的年龄切点。

材料与方法

这是一项对年龄≥40岁的创伤患者进行的回顾性队列和预后分析研究。患者数据从宋卡王子大学医学院附属医院的创伤登记数据库和医院信息系统中检索。根据创伤登记数据计算出估计样本量为1509例患者。将死亡率最高的年龄用作定义老年人群的切点。分析医院费用、重症监护病房(ICU)住院时间、性别、合并症、损伤机制、损伤严重程度评分(ISS)以及创伤和损伤严重程度评分与死亡率的任何相关性,以及它们是否与老年创伤患者相关。

结果

本研究共纳入1523例年龄≥40岁的创伤患者。生存组和死亡组的中位年龄均为61岁,两组性别相似(P值=0.259)。在多因素逻辑回归分析中,调整后的优势比(OR)显示年龄增加与死亡率显著相关(OR=1.05;95%置信区间,1.02 - 1.07;P值<0.001)。在70至79岁和>80岁年龄组中,死亡几率显著增加(OR分别为3.29,95%置信区间,1.24 - 8.68;P值=0.016和OR 3.29,95%置信区间,1.27 - 12.24;P值=0.018)。

结论

年龄是创伤患者死亡的重要危险因素。70岁及以上年龄时死亡率显著增加。

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Age as the Impact on Mortality Rate in Trauma Patients.年龄对创伤患者死亡率的影响
Crit Care Res Pract. 2022 Oct 26;2022:2860888. doi: 10.1155/2022/2860888. eCollection 2022.

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