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老年是创伤患者住院死亡率增加的标准:一项回顾性队列研究。

The elderly age criterion for increased in-hospital mortality in trauma patients: a retrospective cohort study.

机构信息

Department of Emergency Medicine, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, Republic of Korea.

Biostatistics Collaboration Unit, Department of Biomedical Systems Informatics, Yonsei University College of Medicine, Seoul, Republic of Korea.

出版信息

Scand J Trauma Resusc Emerg Med. 2021 Sep 10;29(1):133. doi: 10.1186/s13049-021-00950-x.

Abstract

BACKGROUND

With an aging population, the number of elderly individuals exposed to traumatic injuries is increasing. The elderly age criterion for traumatic injuries has been inconsistent in the literature. This study aimed at specifying the elderly age criterion when the traumatic mortality rate increases.

METHODS

This is a multicenter retrospective cohort study that was conducted utilizing the data from the Emergency Department-based Injury In-depth Surveillance Registry of the Korea Disease Control and Prevention Agency, collected between January 2014 and December 2018 from 23 emergency departments. The outcome variable was in-hospital mortality. Multivariable logistic regression analysis was used to calculate the adjusted mortality rate for each age group. By using the shape-restricted regression splines method, the relationship between age and adjusted traumatic mortality was plotted and the point where the gradient of the graph had the greatest variation was calculated.

RESULTS

A total of 637,491 adult trauma patients were included. The number of in-hospital deaths was 6504 (1.0%). The age at which mortality increased the most was 65.06 years old. The adjusted odds ratio for the in-hospital mortality rate with age in the ≤ 64-year-old subgroup was 1.038 (95% confidence interval (CI) 1.032-1.044) and in the ≥ 65-year-old subgroup was 1.059 (95% CI 1.050-1.068). The adjusted odds ratio for in-hospital mortality in the ≥ 65-year-old compared to the ≤ 64-year-old subgroup was 4.585 (95% CI 4.158-5.055, p < 0.001).

CONCLUSIONS

This study found that the in-hospital mortality rate rose with increasing age and that the increase was the most rapid from the age of 65 years. We propose to define the elderly age criterion for traumatic injuries as ≥ 65 years of age.

摘要

背景

随着人口老龄化,遭受创伤的老年人数量不断增加。创伤死亡率增加的老年年龄标准在文献中并不一致。本研究旨在确定创伤死亡率增加时的老年年龄标准。

方法

这是一项多中心回顾性队列研究,利用韩国疾病控制与预防署基于急诊科的伤害深入监测登记处的数据,于 2014 年 1 月至 2018 年 12 月期间从 23 个急诊科收集。结局变量为住院死亡率。使用多变量逻辑回归分析计算每个年龄组的调整死亡率。通过使用形状受限回归样条方法,绘制年龄与调整后创伤死亡率之间的关系,并计算图形梯度变化最大的点。

结果

共纳入 637491 名成人创伤患者。住院死亡人数为 6504 人(1.0%)。死亡率增加最多的年龄是 65.06 岁。≤64 岁亚组中年龄与住院死亡率的调整比值比为 1.038(95%置信区间 1.032-1.044),≥65 岁亚组为 1.059(95%置信区间 1.050-1.068)。与≤64 岁亚组相比,≥65 岁亚组的住院死亡率调整比值比为 4.585(95%置信区间 4.158-5.055,p<0.001)。

结论

本研究发现,住院死亡率随年龄增长而上升,从 65 岁开始上升最快。我们建议将创伤的老年年龄标准定义为≥65 岁。

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