Resasco Agustina, Diaz Silvina Laura
Instituto de Biología Celular y Neurociencia (UBA - CONICET), Facultad de Medicina, Universidad de Buenos Aires, Ciudad Autónoma de Buenos Aires, Argentina.
Laboratorio de Animales de Experimentación (LAE), Facultad de Ciencias Veterinarias, Universidad Nacional de La Plata, La Plata, Argentina.
Front Vet Sci. 2022 Oct 20;9:1031976. doi: 10.3389/fvets.2022.1031976. eCollection 2022.
The science and technology of laboratory animals has come a long way worldwide, but for reasons related to the development of the countries, this journey started later in some Latin American countries, as is the case of Argentina. Without a specific legal framework to conduct animal experimentation, local strengths to promote animal welfare are based on professionals specifically trained in the care of laboratory animals as well as an extended network of ethics committees that ensures compliance with the ethical principles applied to animal experimentation. Nevertheless, there are no updated reports showing welfare indicators in rodent facilities. Therefore, we conducted a survey on mice breeding facilities enrolled in a national record elaborated by the National Ministry of Science. Questions related to four of the Five Domains Model of Mellor, concerning (1) nutrition, (2) physical environment, (3) health, and (4) behavioral interactions with the environment, other animals, and humans, were included as well as information concerning general aspects of the establishments. Data obtained from 25 mice breeder facilities localized all over the country were summarized, providing for the first time a clear picture of the national situation about the welfare of laboratory mice in these establishments. This data will be essential to design future policy as well as for deciding priorities aiming to improve the welfare of mice bred in Argentinian facilities.
在全球范围内，实验动物科学技术已经取得了长足的进步，但由于各国发展情况不同，在一些拉丁美洲国家，比如阿根廷，这一进程起步较晚。由于缺乏进行动物实验的具体法律框架，当地促进动物福利的优势在于有经过专门培训的照顾实验动物的专业人员，以及确保遵守动物实验伦理原则的广泛的伦理委员会网络。然而，目前尚无关于啮齿动物设施福利指标的最新报告。因此，我们对列入国家科学部编制的国家记录中的小鼠繁殖设施进行了一项调查。调查问题包括梅勒五域模型中的四个方面，即（1）营养、（2）物理环境、（3）健康以及（4）与环境、其他动物和人类的行为互动，同时还包括有关这些设施一般情况的信息。对从全国25个小鼠繁殖设施收集到的数据进行了汇总，首次清晰地呈现了这些设施中实验小鼠福利的全国状况。这些数据对于制定未来政策以及确定旨在改善阿根廷设施中繁殖小鼠福利的优先事项至关重要。
