Mohamed Mohamed M G, Jadhav Amar, Banuelos Polo, Lacasse Alexandre, Kumar Vikas
Internal Medicine Department, SSM Health St. Mary's Hospital, St. Louis, Missouri.
Critical Care Medicine, SSM Health St. Mary's Hospital, St. Louis, Missouri.
Proc (Bayl Univ Med Cent). 2022 Jul 13;35(6):871-873. doi: 10.1080/08998280.2022.2096348. eCollection 2022.
Neurological complications following SARS-CoV-2 infections are increasingly recognized. Despite that, sequelae from SARS-CoV-2 infection in gravid women are uncommonly reported. We present a case of acute motor axonal neuropathy, a variant of Guillain-Barre syndrome, in a 26-year-old primigravida at 34 weeks' gestation. She presented with worsening diplopia, dysphagia, and lower extremity sensory and motor deficits after testing positive for SARS-CoV-2 2 weeks earlier. Due to rapidly progressive symptoms, she required endotracheal intubation and mechanical ventilation. Initially she was diagnosed with Miller Fisher syndrome, but serology and electromyography studies were consistent with acute motor axonal neuropathy. Spontaneous preterm delivery, supportive care, and intravenous immunoglobulin therapy resulted in clinical improvement. Steady recovery was achieved by a prolonged rehabilitation program.
新型冠状病毒2（SARS-CoV-2）感染后的神经系统并发症越来越受到关注。尽管如此，关于妊娠女性感染SARS-CoV-2后的后遗症却鲜有报道。我们报告一例急性运动轴索性神经病，这是格林-巴利综合征的一种变体，发生在一名26岁、孕34周的初产妇身上。她在2周前新型冠状病毒检测呈阳性后，出现了复视加重、吞咽困难以及下肢感觉和运动功能障碍。由于症状迅速进展，她需要进行气管插管和机械通气。最初她被诊断为米勒-费雪综合征，但血清学和肌电图检查结果与急性运动轴索性神经病相符。自然早产、支持性治疗以及静脉注射免疫球蛋白治疗使病情得到了临床改善。通过长期的康复计划实现了稳步康复。
