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Clozapine Is Severely Underused in Parkinson's Disease Patients.

作者信息

Friedman Joseph H

机构信息

Movement Disorders Program Butler Hospital Blackstone Blvd Providence Rhode Island USA.

Department of Neurology Warren Alpert Medical School of Brown University Providence Rhode Island USA.

出版信息

Mov Disord Clin Pract. 2022 Oct 23;9(8):1021-1024. doi: 10.1002/mdc3.13582. eCollection 2022 Nov.

DOI:10.1002/mdc3.13582
PMID:36339313
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9631840/
Abstract
摘要

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Clozapine Use in a Movement Disorder Clinic.氯氮平在运动障碍诊所的应用。
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Neuropsychiatric disorders in Parkinson's disease.帕金森病中的神经精神障碍
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Sedation and sleep safety of pimavanserin for Parkinsons's disease psychosis: Review and exploratory analysis of clinical study data.匹莫范色林用于帕金森病精神病的镇静作用及睡眠安全性：临床研究数据回顾与探索性分析
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Clozapine for Quetiapine-Refractory Psychosis in Parkinson's Disease: A Long-Term Single-Center Retrospective Study.氯氮平治疗帕金森病中对喹硫平难治性精神病：一项长期单中心回顾性研究。
Parkinsons Dis. 2025 Mar 10;2025:1068722. doi: 10.1155/padi/1068722. eCollection 2025.
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Rethinking Clozapine: Lights and Shadows of a Revolutionary Drug.重新审视氯氮平：一种革命性药物的利弊
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本文引用的文献

1
Clozapine Use in a Movement Disorder Clinic.氯氮平在运动障碍诊所的应用。
Clin Neuropharmacol. 2022;45(4):95-98. doi: 10.1097/WNF.0000000000000510. Epub 2022 Jun 11.
2
Comparative effectiveness of antipsychotic monotherapy and polypharmacy in schizophrenia patients with clozapine treatment: A nationwide, health insurance data-based study.氯氮平治疗的精神分裂症患者中抗精神病药物单一疗法与联合用药的比较疗效：一项基于全国医疗保险数据的研究。
Eur Neuropsychopharmacol. 2022 Jun;59:36-44. doi: 10.1016/j.euroneuro.2022.03.010. Epub 2022 May 9.
3
Hallucinations and delusions associated with Parkinson's disease psychosis: safety of current treatments and future directions.与帕金森病精神病相关的幻觉和妄想：当前治疗方法的安全性及未来方向
Expert Opin Drug Saf. 2022 Jul;21(7):873-879. doi: 10.1080/14740338.2022.2069240. Epub 2022 May 3.
4
Absolute Agranulocytosis After 9 Weeks of Clozapine 25 mg Daily.氯氮平每日 25mg 治疗 9 周后出现全血细胞减少症。
Clin Neuropharmacol. 2022;45(1):9-10. doi: 10.1097/WNF.0000000000000491.
5
Falls and Fractures in Patients with Parkinson's Disease-Related Psychosis Treated with Pimavanserin vs Atypical Antipsychotics: A Cohort Study.匹莫范色林与非典型抗精神病药物治疗帕金森病相关精神病患者的跌倒与骨折：一项队列研究
Drugs Real World Outcomes. 2022 Mar;9(1):9-22. doi: 10.1007/s40801-021-00284-1. Epub 2021 Oct 30.
6
Risk of Hospitalization and Death Associated With Pimavanserin Use in Older Adults With Parkinson Disease.与帕金森病老年患者使用 pimavanserin 相关的住院和死亡风险。
Neurology. 2021 Sep 28;97(13):e1266-e1275. doi: 10.1212/WNL.0000000000012601. Epub 2021 Aug 13.
7
Low continuation of antipsychotic therapy in Parkinson disease - intolerance, ineffectiveness, or inertia?抗精神病药物治疗帕金森病的持续时间不足——不耐受、无效还是惯性？
BMC Neurol. 2021 Jun 24;21(1):240. doi: 10.1186/s12883-021-02265-x.
8
An evaluation of the variation and underuse of clozapine in the United Kingdom.评估氯氮平在英国的变异和未充分利用情况。
Acta Psychiatr Scand. 2021 Apr;143(4):339-347. doi: 10.1111/acps.13280. Epub 2021 Feb 9.
9
Efficacy and safety of atypical antipsychotics for psychosis in Parkinson's disease: A systematic review and Bayesian network meta-analysis.非典型抗精神病药治疗帕金森病精神病的疗效和安全性：系统评价和贝叶斯网状meta 分析。
Parkinsonism Relat Disord. 2020 Sep;78:82-90. doi: 10.1016/j.parkreldis.2020.07.021. Epub 2020 Jul 24.
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Risk of Mortality Associated With Atypical Antipsychotic use: A National Cohort Study of Older Adults With Depression and Parkinson's Disease.与使用非典型抗精神病药物相关的死亡风险：一项针对老年抑郁症和帕金森病患者的全国队列研究。
Am J Geriatr Psychiatry. 2020 Oct;28(10):1079-1088. doi: 10.1016/j.jagp.2020.01.193. Epub 2020 Feb 7.