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可折叠囊状玻璃体在严重眼外伤及硅油依赖眼中的临床应用

Clinical Application of Foldable Capsular Vitreous Bodies in the Treatment of Severe Ocular Trauma and Silicone Oil Dependent Eyes.

作者信息

Jiang Hao, Xue Chao, Gao Yanlin, Chen Ying, Wang Yan

机构信息

Tianjin Eye Hospital, Tianjin Key Laboratory of Ophthalmology and Visual Science, Tianjin Eye Institute, Tianjin, China.

Nankai University Affiliated Eye Hospital, Nankai University, Tianjin, China.

出版信息

J Ophthalmol. 2022 Oct 28;2022:3608162. doi: 10.1155/2022/3608162. eCollection 2022.

Abstract

PURPOSE

This study aimed to assess the application of a foldable capsular vitreous body (FCVB) in the treatment of severe ocular trauma and silicone oil (SO) dependent eyes.

METHODS

A retrospective analysis was performed on the clinical application of FCVB in the treatment of severe ocular trauma and SO dependent eyes. The results of best-corrected visual acuity and intraocular pressure (IOP) evaluation, B-scan ultrasonography or color Doppler ultrasonography, ultrasound biomicroscopy, and anterior segment photography were recorded during follow-up. A paired -test was used to compare the difference in IOP before and after FCVB implantation.

RESULTS

Seven eyes of seven patients were included in the 6-month follow-up. In all cases, B-scan ultrasonography and ultrasound biomicroscopy showed that FCVB adapted closely to the globe wall and ciliary body, thus supporting the retina. Visual acuity did not improve, except in one case from LP to HM. The mean ± SD IOP was 8.5 ± 1.90 mm·Hg prior to FCVB implantation and 10.43 ± 0.98 mm·Hg after implantation, with no significant difference between these measurements (=0.095). Five of the seven patients developed differing degrees of corneal opacity and keratopathy.

CONCLUSIONS

FCVB implantation may be a safe and effective method for the treatment of severe ocular trauma and SO dependent eyes. However, FCVB cannot prevent the phthisis of the traumatic eyes. In addition, corneal opacity and keratopathy are potentially serious complications after surgery. Appropriate case selection and proper surgical timing are required for further investigation.

摘要

目的

本研究旨在评估可折叠式人工玻璃体球囊(FCVB)在严重眼外伤及硅油依赖眼中的应用。

方法

对FCVB治疗严重眼外伤及硅油依赖眼的临床应用进行回顾性分析。随访期间记录最佳矫正视力、眼压(IOP)评估结果、B超或彩色多普勒超声、超声生物显微镜检查及眼前节照相结果。采用配对t检验比较FCVB植入前后眼压的差异。

结果

7例患者的7只眼纳入6个月随访。所有病例中,B超和超声生物显微镜检查显示FCVB与眼球壁及睫状体紧密贴合,从而支撑视网膜。除1例视力从光感提高到手动外,视力无改善。FCVB植入前平均眼压±标准差为8.5±1.90mmHg,植入后为10.43±0.98mmHg,两者差异无统计学意义(P=0.095)。7例患者中有5例出现不同程度的角膜混浊和角膜病变。

结论

FCVB植入可能是治疗严重眼外伤及硅油依赖眼的一种安全有效的方法。然而,FCVB不能防止外伤眼的眼球痨。此外,角膜混浊和角膜病变是术后潜在的严重并发症。需要进一步研究合适的病例选择和恰当的手术时机。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a9ed/9635962/939988dcd4b3/JOPH2022-3608162.001.jpg

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