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行为毒理学中活动测量方法的应用。

Use of activity measures in behavioral toxicology.

作者信息

Reiter L

出版信息

Environ Health Perspect. 1978 Oct;26:9-20. doi: 10.1289/ehp.78269.

Abstract

Locomotor activity measurements have been used extensively to evaluate chemically-induced changes in CNS function. This paper focuses on several factors including apparatus, age, biological rhythm, and social setting, which influence both locomotor activity levels per se and chemically induced changes in these activity levels. These data illustrate that failure to recognize, specify, and consider these factors is likely to result in equivocal studies subject to possible misinterpretation.

摘要

运动活动测量已被广泛用于评估化学物质诱导的中枢神经系统功能变化。本文重点关注几个因素,包括仪器、年龄、生物节律和社会环境,这些因素既影响运动活动水平本身,也影响化学物质诱导的这些活动水平的变化。这些数据表明,未能识别、明确和考虑这些因素可能会导致研究结果模棱两可,容易产生误解。

相似文献

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Use of activity measures in behavioral toxicology.行为毒理学中活动测量方法的应用。
Environ Health Perspect. 1978 Oct;26:9-20. doi: 10.1289/ehp.78269.
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本文引用的文献

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Circadian chronopharmacology.昼夜节律时辰药理学
Annu Rev Pharmacol. 1971;11:455-92. doi: 10.1146/annurev.pa.11.040171.002323.
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Amphetamine as a model for hyperactivity in the rat.苯丙胺作为大鼠多动的模型。
Physiol Behav. 1973 Aug;11(2):181-6. doi: 10.1016/0031-9384(73)90348-x.
10
Development of nocturnal behavior in albino rats.白化大鼠夜间行为的发展。
Behav Biol. 1975 Nov;15(3):317-31. doi: 10.1016/s0091-6773(75)91717-4.

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