Suppr超能文献

ST段抬高型心肌梗死患者的护理:对欧洲观察性研究项目急性冠状动脉综合征STEMI注册研究以及欧洲心脏病学会的ACVC和EAPCI协会中11462例患者质量指标的国际分析。

Care of patients with ST-elevation myocardial infarction: an international analysis of quality indicators in the acute coronary syndrome STEMI Registry of the EURObservational Research Programme and ACVC and EAPCI Associations of the European Society of Cardiology in 11 462 patients.

作者信息

Ludman Peter, Zeymer Uwe, Danchin Nicolas, Kala Petr, Laroche Cécile, Sadeghi Masoumeh, Caporale Roberto, Shaheen Sameh Mohamed, Legutko Jacek, Iakobishvili Zaza, Alhabib Khalid F, Motovska Zuzana, Studencan Martin, Mimoso Jorge, Becker David, Alexopoulos Dimitrios, Kereseselidze Zviad, Stojkovic Sinisa, Zelveian Parounak, Goda Artan, Mirrakhimov Erkin, Bajraktari Gani, Farhan Hasan Ali, Šerpytis Pranas, Raungaard Bent, Marandi Toomas, Moore Alice May, Quinn Martin, Karjalainen Pasi Paavo, Tatu-Chitoiu Gabriel, Gale Chris P, Maggioni Aldo P, Weidinger Franz

机构信息

Institute of Cardiovascular Sciences, University of Birmingham, Birmingham, UK.

Klinikum der Stadt Ludwigshafen and Institut für Herzinfarktforschung, Ludwigshafen am Rhein, Germany.

出版信息

Eur Heart J Acute Cardiovasc Care. 2023 Jan 27;12(1):22-37. doi: 10.1093/ehjacc/zuac143.

Abstract

AIMS

To use quality indicators to study the management of ST-segment elevation myocardial infarction (STEMI) in different regions.

METHODS AND RESULTS

Prospective cohort study of STEMI within 24 h of symptom onset (11 462 patients, 196 centres, 26 European Society of Cardiology members, and 3 affiliated countries). The median delay between arrival at a percutaneous cardiovascular intervention (PCI) centre and primary PCI was 40 min (interquartile range 20-74) with 65.8% receiving PCI within guideline recommendation of 60 min. A third of patients (33.2%) required transfer from their initial hospital to one that could perform emergency PCI for whom only 27.2% were treated within the quality indicator recommendation of 120 min. Radial access was used in 56.6% of all primary PCI, but with large geographic variation, from 76.4 to 9.1%. Statins were prescribed at discharge to 98.7% of patients, with little geographic variation. Of patients with a history of heart failure or a documented left ventricular ejection fraction ≤40%, 84.0% were discharged on an angiotensin-converting enzyme inhibitor/angiotensin receptor blocker and 88.7% were discharged on beta-blockers.

CONCLUSION

Care for STEMI shows wide geographic variation in the receipt of timely primary PCI, and is in contrast with the more uniform delivery of guideline-recommended pharmacotherapies at time of hospital discharge.

摘要

目的

运用质量指标研究不同地区ST段抬高型心肌梗死(STEMI)的管理情况。

方法与结果

对症状发作24小时内的STEMI患者进行前瞻性队列研究(11462例患者,196个中心,26个欧洲心脏病学会成员及3个附属国家)。到达经皮心血管介入治疗(PCI)中心至首次PCI的中位延迟时间为40分钟(四分位间距20 - 74),65.8%的患者在指南推荐的60分钟内接受了PCI。三分之一的患者(33.2%)需要从初始医院转至能进行急诊PCI的医院,其中只有27.2%的患者在质量指标推荐的120分钟内接受了治疗。所有首次PCI中56.6%采用桡动脉入路,但存在较大的地域差异,从76.4%至9.1%不等。出院时98.7%的患者接受了他汀类药物治疗,地域差异较小。有心力衰竭病史或记录的左心室射血分数≤40%的患者中,84.0%出院时使用了血管紧张素转换酶抑制剂/血管紧张素受体阻滞剂,88.7%出院时使用了β受体阻滞剂。

结论

STEMI的治疗在及时接受首次PCI方面存在广泛的地域差异,这与出院时指南推荐的药物治疗更为统一的实施情况形成对比。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验