Stanciugelu Alexandra, Petrică Alina, Chiriac Sorin Dan, Iurciuc Mircea, Boruga Madalina Veronica, Balica Nicolae, Mederle Ovidiu Alexandru
Department of Surgery, Faculty of Medicine, 'Victor Babes' University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Department of Emergency, Emergency Clinical Municipal Hospital, 300079 Timisoara, Romania.
Exp Ther Med. 2022 Oct 24;24(6):730. doi: 10.3892/etm.2022.11666. eCollection 2022 Dec.
Budd-Chiari syndrome (BCS) is a rare disorder clinically characterized by abdominal pain, hepatomegaly and ascites. The condition is often related to thrombosis of the hepatic veins or the terminal portion of the inferior vena cava. A myeloproliferative disorder is the most identified underlying prothrombotic risk factor, although almost one-half of affected patients are now recognized as having multiple underlying prothrombotic risk factors. Doppler ultrasound may be enough to confirm the diagnosis of BCS; however, computed tomography or magnetic resonance imaging is often employed. Anticoagulant therapy is the cornerstone of BCS treatment, but most patients also need additional treatment strategies. Most patients with BCS are now treated by endovascular intervention, which has improved survival rate in those afflicted by this disease. The long-term course of the disease can be complicated by progression or recurrence of the underlying myeloproliferative disorder. The present study reports the cases of two patients with BCS with the aim of alerting healthcare workers in Emergency Departments of this less common diagnosis in patients presenting with frequent complaints of abdominal pain.
布加综合征（BCS）是一种罕见的疾病，临床特征为腹痛、肝肿大和腹水。该病常与肝静脉或下腔静脉末端血栓形成有关。骨髓增殖性疾病是最常见的潜在促血栓形成危险因素，尽管现在几乎一半的患者被认为有多种潜在促血栓形成危险因素。多普勒超声可能足以确诊BCS；然而，计算机断层扫描或磁共振成像也经常被采用。抗凝治疗是BCS治疗的基石，但大多数患者还需要其他治疗策略。现在大多数BCS患者通过血管内介入治疗，这提高了该病患者的生存率。该疾病的长期病程可能因潜在骨髓增殖性疾病的进展或复发而复杂化。本研究报告了两例BCS患者的病例，目的是提醒急诊科的医护人员，对于经常主诉腹痛的患者，这种不太常见的诊断。
