Adamik Juraj, Butterfield Lisa H
Parker Institute for Cancer Immunotherapy, University of California, San Francisco, Suite D3500, 1 Letterman Drive, San Francisco, CA 94129, USA.
Sci Transl Med. 2022 Nov 9;14(670):eabo4632. doi: 10.1126/scitranslmed.abo4632.
Cancer vaccines have been shown clinically to drive tumor-reactive cell activation, proliferation, and effector function. Unfortunately, tumor eradication by treatment with cancer vaccines has been unsuccessful in many patients. Critical steps are under way to improve vaccine efficacy and combine them with immunotherapy and standard-of-care treatments.
癌症疫苗已在临床上显示出能驱动肿瘤反应性细胞的激活、增殖和效应功能。不幸的是，许多患者通过癌症疫苗治疗根除肿瘤的尝试均未成功。目前正在采取关键步骤来提高疫苗疗效，并将其与免疫疗法及标准治疗方法相结合。
