Williams Craig R, Webb Cameron E, Higgs Stephen, van den Hurk Andrew F
UniSA: Clinical and Health Sciences, University of South Australia, Adelaide, South Australia, Australia.
Medical Entomology, NSW Health Pathology, Westmead, New South Wales, Australia.
Vector Borne Zoonotic Dis. 2022 Nov;22(11):529-534. doi: 10.1089/vbz.2022.0037. Epub 2022 Oct 10.
Japanese encephalitis virus (JEV) continues to cause significant numbers of human infections and fatalities despite the availability of efficacious vaccines. It is regarded as an emerging mosquito-borne pathogen with the potential of introduction into many countries. In 2022, JEV was detected in Australia on a hitherto unprecedented scale, with local transmission by indigenous mosquitoes to amplifying swine hosts and to humans. In this study, we review this recent disease activity, propose possible routes of virus movement, ecological drivers of activity, and consider possible future transmission scenarios. Measures to enhance current surveillance systems and potential strategies for health authorities to minimize future risks are discussed.
尽管有有效的疫苗，但日本脑炎病毒（JEV）仍继续导致大量人类感染和死亡。它被视为一种新兴的蚊媒病原体，有可能传入许多国家。2022年，澳大利亚以前所未有的规模检测到JEV，当地的本土蚊子将病毒传播给了作为扩增宿主的猪以及人类。在本研究中，我们回顾了近期的疾病活动情况，提出了病毒传播的可能途径、活动的生态驱动因素，并考虑了未来可能的传播情景。还讨论了加强当前监测系统的措施以及卫生当局将未来风险降至最低的潜在策略。
