Vrielinck Joris, Janssens Geert P J, Chantziaras Ilias, Cools An, Maes Dominiek
Faculty of Veterinary Medicine, Ghent University, 9000 Ghent, Belgium.
Veterinary Practice, Hospitaalstraat 38, 8906 Ieper-Elverdinge, Belgium.
Vet Sci. 2022 Nov 6;9(11):614. doi: 10.3390/vetsci9110614.
The present study investigated whether dietary supplementation of tripotassium citrate or NaCl reduced the prevalence of calcium oxalate dihydrate (COD) uroliths in fattening pigs on a farm with a high prevalence of COD uroliths. Each group (control, TPC, NaCl) consisted of three batches of approximately 260 fattening pigs each. Performance, water intake, markers for bone resorption (CTX) and bone formation (osteocalcin) and urinalysis from samples taken at the farm and in the slaughterhouse were investigated. Performance parameters, feed and water intake, CTX and osteocalcin were not significantly different between the groups (p > 0.05). The main crystals found were struvite, COD, calcite and amorphous crystals. The prevalence of COD crystals was lower in samples from the slaughterhouse in each group. Microscopic and biochemical examination of urine showed large differences between samples from the farm and the slaughterhouse. In conclusion, there were no beneficial effects of feed supplementation with TPC or NaCl on the prevalence of COD crystals but TPC has a clear promoting influence on the development of alkaline calcite crystals. Urinalysis from samples taken at the slaughterhouse does not fully reflect the situation on the farm.
本研究调查了在一水合草酸钙（COD）尿石症高发猪场，日粮中添加柠檬酸钾或氯化钠是否能降低育肥猪COD尿石症的发病率。每组（对照组、TPC组、氯化钠组）由三批各约260头育肥猪组成。对猪场和屠宰场采集的样本进行了生产性能、饮水量、骨吸收标志物（CTX）和骨形成标志物（骨钙素）以及尿液分析。各组之间的生产性能参数、采食量和饮水量、CTX和骨钙素无显著差异（p>0.05）。发现的主要晶体为鸟粪石、COD、方解石和无定形晶体。每组屠宰场样本中COD晶体的发病率较低。尿液的显微镜检查和生化检查显示，猪场和屠宰场的样本存在很大差异。总之，日粮中添加TPC或氯化钠对COD晶体的发病率没有有益影响，但TPC对碱性方解石晶体的形成有明显的促进作用。屠宰场采集样本的尿液分析不能完全反映猪场的情况。
