Li Changcheng, Xu Ziheng, Chen Wenyan, Zhou Chenyu, Wang Can, Wang Min, Liang Jingzhen, Wei Ping
Institute for Poultry Science and Health, Guangxi University, Nanning 530004, China.
School of Public Health and Management, Guang University of Chinese Medical, Nanning 530200, China.
Antibiotics (Basel). 2022 Nov 9;11(11):1579. doi: 10.3390/antibiotics11111579.
is capable of harming human and animal health, and its multidrug resistance (MDR) has always been a public health problem. In addition, antibiotic-free or antibiotic-reduced policies have been implemented in poultry production. Therefore, the search for antibiotic alternatives is more urgent than ever before. The aim of this study was to assess the antibacterial activity of star anise-cinnamon essential oil (SCEO) in vitro and its prophylactic effect against the infections of , , and in vivo. The results demonstrated that SCEO is effective against , , and in vitro. Supplementation with SCEO could significantly decrease the infections of and , whereas it could slightly but not significantly decrease the infection of , while also significantly alleviating the body weight (BW) loss caused by the infections of , , and in Yellow chickens. The SCEO had the best prophylactic effect against the infection of in Yellow chickens, followed by the infection of and the infection of . The SCEO, used as an antibiotic alternative, could be an effective prevention strategy against the infections of , , and in Yellow chickens.
能够危害人类和动物健康，其多重耐药性（MDR）一直是一个公共卫生问题。此外，家禽生产中已实施无抗生素或减少抗生素使用的政策。因此，寻找抗生素替代品比以往任何时候都更加紧迫。本研究的目的是评估八角茴香-肉桂精油（SCEO）的体外抗菌活性及其对黄羽鸡体内感染大肠杆菌、沙门氏菌和金黄色葡萄球菌的预防作用。结果表明，SCEO在体外对大肠杆菌、沙门氏菌和金黄色葡萄球菌有效。添加SCEO可显著降低大肠杆菌和沙门氏菌的感染率，而对金黄色葡萄球菌感染率的降低作用较小但不显著，同时还能显著减轻黄羽鸡因感染大肠杆菌、沙门氏菌和金黄色葡萄球菌而导致的体重损失。SCEO对黄羽鸡金黄色葡萄球菌感染的预防效果最佳，其次是沙门氏菌感染和大肠杆菌感染。SCEO作为抗生素替代品，可能是预防黄羽鸡感染大肠杆菌、沙门氏菌和金黄色葡萄球菌的有效策略。
