Van Hoornweder Sybren, Blanco-Mora Diego Andres, Depestele Siel, van Dun Kim, Cuypers Koen, Verstraelen Stefanie, Meesen Raf
REVAL-Rehabilitation Research Center, Faculty of Rehabilitation Sciences, University of Hasselt, 3590 Diepenbeek, Belgium.
Faculty of Medicine, University of Lisbon, 1000 Lisbon, Portugal.
Brain Sci. 2022 Oct 26;12(11):1444. doi: 10.3390/brainsci12111444.
With aging comes degradation of bimanual movement performance. A hallmark feature of bimanual movements is movement-related beta desynchronization (MRBD), an attenuation in the amplitude of beta oscillations associated with sensorimotor activation. Here, we investigated MRBD in 39 healthy adults (20 younger and 19 older adults) in frontal, central, and parietal regions across both hemispheres, during the planning and execution of a bimanual tracking task. Task accuracy decreased with age and during more difficult conditions when both hands had to move at different relative speeds. MRBD was mostly situated in the central region, and increased in older versus younger adults during movement execution but not planning. Irrespective of age, motor planning and execution were associated with increased MRBD in the left and right hemispheres, respectively. Notably, right central MRBD during motor planning was associated with bimanual task performance, particularly in older adults. Specifically, persons who demonstrated high MRBD during motor planning performed better on the bimanual tracking task. Our results highlight the importance of lateralized MRBD during motor planning, thereby shining new light on previous research and providing a promising avenue for future interventions.
随着年龄增长，双手协调性运动表现会出现退化。双手协调性运动的一个标志性特征是与运动相关的β波去同步化（MRBD），即与感觉运动激活相关的β振荡幅度衰减。在此，我们在一项双手跟踪任务的计划和执行过程中，对39名健康成年人（20名年轻人和19名老年人）双侧半球的额叶、中央和顶叶区域的MRBD进行了研究。任务准确性随着年龄增长而下降，并且在双手必须以不同相对速度移动的更困难条件下也会下降。MRBD主要位于中央区域，在运动执行过程中，老年人的MRBD相对于年轻人有所增加，但在计划阶段没有增加。无论年龄如何，运动计划和执行分别与左右半球MRBD的增加有关。值得注意的是，运动计划期间右侧中央MRBD与双手任务表现相关，尤其是在老年人中。具体而言，在运动计划期间表现出高MRBD的人在双手跟踪任务上表现更好。我们的结果突出了运动计划期间MRBD偏侧化的重要性，从而为先前的研究提供了新的思路，并为未来的干预措施提供了一条有前景的途径。
