Confalonieri Filippo, Haave Hanna, Bragadottir Ragnheidur, Stene-Johansen Ingar, Lumi Xhevat, Lytvynchuk Lyubomyr, Petrovski Goran
Department of Ophthalmology, Oslo University Hospital, Kirkeveien 166, 0450 Oslo, Norway.
Center for Eye Research and Innovative Diagnostics, Department of Ophthalmology, Institute for Clinical Medicine, University of Oslo, Kirkeveien 166, 0450 Oslo, Norway.
Biomedicines. 2022 Nov 9;10(11):2873. doi: 10.3390/biomedicines10112873.
Non-invasive diagnostic technologies in ophthalmology have substantially transformed contemporary clinical practice. Intraoperative optical coherence tomography (iOCT) systems have recently been used for various surgical interventions, including the treatment of full-thickness macular holes (FTMHs).
We conducted a systematic review on the use of iOCT and its possible benefits in the management of FTMHs, following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines (PRISMA). The level of evidence according to the Oxford Centre for Evidence-Based Medicine (OCEM) 2011 guidelines, and the quality of evidence according to the Grading of Recommendations Assessment, Development and Evaluation (GRADE) system, were assessed for all included articles.
1131 articles were initially extracted, out of which 694 articles were obtained after duplicates were removed and their abstracts screened. A total of 65 articles was included for full-text review. Finally, 17 articles remained that fulfilled the inclusion criteria.
Even though there is just a small number of studies with solid results, the use of iOCT in FTMH surgery may be a helpful tool for both novice and experienced surgeons planning and managing difficult cases. Additionally, it could be used for teaching reasons and for exploring novel surgical techniques.
眼科中的非侵入性诊断技术已极大地改变了当代临床实践。术中光学相干断层扫描（iOCT）系统最近已用于各种手术干预，包括全层黄斑裂孔（FTMH）的治疗。
我们按照系统评价和荟萃分析的首选报告项目（PRISMA）指南，对iOCT在FTMH管理中的应用及其可能的益处进行了系统评价。根据牛津循证医学中心（OCEM）2011年指南评估证据水平，并根据推荐分级评估、制定和评价（GRADE）系统评估所有纳入文章的证据质量。
最初提取了1131篇文章，去除重复文章并筛选摘要后，获得了694篇文章。总共65篇文章被纳入全文评审。最后，有17篇文章符合纳入标准。
尽管只有少数研究有确凿结果，但在FTMH手术中使用iOCT对于计划和处理疑难病例的新手和经验丰富的外科医生可能都是一个有用的工具。此外，它可用于教学目的以及探索新的手术技术。
