Department of Physical and Biocoordination Chemistry, Medical University of Lodz, Muszyńskiego 1, 90-151 Lodz, Poland.
Department of Biochemistry, Medical University of Lodz, Mazowiecka 5, 92-215 Lodz, Poland.
Molecules. 2022 Oct 25;27(21):7226. doi: 10.3390/molecules27217226.
In the present study, the complexing properties of ceftazidime with Fe(III) ions in aqueous solutions were characterized by UV-vis spectrophotometric and potentiometric methods. Using the UV-vis spectrophotometric method, the absorbance values for Fe(III) ions, a third-generation cephalosporin antibiotic (ceftazidime), and the Fe(III)-ceftazidime system were determined. Based on pH-metric studies, the value of the stability constant for the Fe(III)-ceftazidime complex was calculated.
在本研究中，采用紫外可见分光光度法和电位法研究了头孢他啶与 Fe(III)离子在水溶液中的配位性质。利用紫外可见分光光度法，测定了 Fe(III)离子、第三代头孢菌素抗生素（头孢他啶）和 Fe(III)-头孢他啶体系的吸光度值。基于 pH 滴定研究，计算了 Fe(III)-头孢他啶配合物的稳定常数值。
