Umbreit Jay
Division of Hematology/Oncology, Winship Cancer Institute, Emory University, Atlanta, GA 30322, USA.
Am J Hematol. 2005 Mar;78(3):225-31. doi: 10.1002/ajh.20249.
Iron deficiency is a major worldwide health problem. There is recent evidence that the anemia is only the last manifestation of the syndrome and that symptoms occur before the anemia is manifest. Advances in outlining the physiology of iron deficiency have been made, gaps remain in the current understanding. While oral iron supplement remains the mainstay, some indications for the intravenous administration have developed. This review will highlight the epidemiology, physiology, clinical presentation, and treatment options.
缺铁是一个全球性的主要健康问题。最近有证据表明，贫血只是该综合征的最后表现，症状在贫血显现之前就已出现。虽然在缺铁生理学的概述方面取得了进展，但目前的认识仍存在差距。虽然口服铁补充剂仍然是主要治疗方法，但静脉注射的一些适应症也已出现。本综述将重点介绍缺铁的流行病学、生理学、临床表现和治疗选择。
