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全髋关节置换术中两种连续非骨水泥型股骨柄尺寸的差异:一项比较性生物力学研究及潜在临床意义

Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications.

作者信息

Wang Katherine, Kenanidis Eustathios, Suleman Khurram, Miodownik Mark, Avadi Mahsa, Horne David, Thompson Jonathan, Tsiridis Eleftherios, Moazen Mehran

机构信息

Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK.

Department of Mechanical Engineering, University College London, Torrington Place, London WC1E 7JE, UK - Academic Orthopaedic Department, Papageorgiou General Hospital & CORE Lab at CIRI AUTH, Aristotle University Medical School, University Campus, 54 124 Thessaloniki, Greece.

出版信息

SICOT J. 2022;8:43. doi: 10.1051/sicotj/2022043. Epub 2022 Nov 11.

Abstract

BACKGROUND

Early failure of uncemented femoral stems associated with incorrect sizing is a known postoperative complication. Surgeons are often faced with the question of whether an uncemented stem of adequate stability or a larger-sized stem should be implanted, especially when the proximal femoral cancellous bone is adequate. The biomechanical effect of sub-optimal stem sizing in the femur remains unclear. This study investigated the mechanical behaviour of two sequential sized uncemented stems of the same type.

METHODS

Six laboratory models of synthetic non-osteoporotic femora were randomly divided into two groups and implanted with either a nominal or oversized uncemented hydroxyapatite-coated nonporous titanium collarless stem. Stiffness, uniaxial strain, and pattern of strain distribution were measured under an anatomical one-legged stance.

RESULTS

Oversized stems demonstrated a higher overall stiffness compared to nominal; however, this was not statistically significant. The nominal stem showed a higher strain in the neck and the proximal medial diaphyseal region. The oversized stem showed higher strains in the distal region around the implant tip.

CONCLUSION

Opting to use a larger stem may potentially increase primary stability, thus allowing safer early mobility. However, higher stiffness may lead to stress shielding, bone loss, and thigh pain in the long term. In addition, strains in the diaphysis and the tip of the stem may predispose to periprosthetic fractures, especially in osteoporotic bones, making this a relatable aspect for users and biomechanical loading. Given the wide range of complex factors that need to be considered when choosing stem size in uncemented THA surgery, this study's results should be interpreted cautiously.

摘要

背景

与尺寸选择不当相关的非骨水泥型股骨柄早期失败是一种已知的术后并发症。外科医生经常面临这样的问题,即应植入具有足够稳定性的非骨水泥型股骨柄还是更大尺寸的股骨柄,尤其是当股骨近端松质骨充足时。股骨柄尺寸欠佳在股骨中的生物力学效应仍不清楚。本研究调查了同一类型的两个连续尺寸的非骨水泥型股骨柄的力学行为。

方法

六个合成的非骨质疏松性股骨实验室模型被随机分为两组,并分别植入标称尺寸或超大尺寸的非骨水泥型羟基磷灰石涂层无孔钛无领股骨柄。在解剖学单腿站立姿势下测量刚度、单轴应变和应变分布模式。

结果

与标称尺寸的股骨柄相比,超大尺寸的股骨柄显示出更高的整体刚度;然而,这在统计学上并不显著。标称尺寸的股骨柄在颈部和近端内侧骨干区域显示出更高的应变。超大尺寸的股骨柄在植入物尖端周围的远端区域显示出更高的应变。

结论

选择使用更大尺寸的股骨柄可能会潜在地增加初始稳定性,从而使早期活动更安全。然而,从长远来看,更高的刚度可能会导致应力遮挡、骨质流失和大腿疼痛。此外,骨干和股骨柄尖端的应变可能会使假体周围骨折的风险增加,尤其是在骨质疏松性骨中,这使得这成为使用者和生物力学负荷方面需要考虑的一个相关因素。鉴于在非骨水泥型全髋关节置换手术中选择股骨柄尺寸时需要考虑的复杂因素范围广泛,本研究的结果应谨慎解读。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6f3a/9651064/39d7d028bcc1/sicotj-8-43-fig1.jpg

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