Syrian-Lebanese Hospital, São Paulo, Brazil.
Nutr Cancer. 2023;75(2):582-590. doi: 10.1080/01635581.2022.2139395. Epub 2022 Nov 12.
Coronavirus disease (COVID-19) is a critical and potentially fatal condition. The nutritional status affects the evolution and clinical outcome throughout the disease course among factors influencing the patient prognosis. In patients with cancer, the Patient-Generated Subjective Global Assessment (PG-SGA) is the preferred instrument for assessing the nutritional status. The aim of this retrospective cross-sectional study was to evaluate the impact of the nutritional status on the clinical outcome of patients with COVID-19 undergoing cancer treatment. We enrolled 52 patients with cancer under outpatient follow-up who had been diagnosed with COVID-19 during the cancer treatment course. The PG-SGA instrument revealed age ( = 0.045) and nutritional status ( = 0.042) before infection as the main risk factors of death from COVID-19. In addition, the risk of mortality due to COVID-19 increased with the degree of malnutrition. Twelve (23.1%) of the 52 patients showed no negative effects related to COVID-19, and age below 65 years was considered to be a protective factor.
冠状病毒病(COVID-19)是一种严重且可能致命的疾病。在影响患者预后的诸多因素中,营养状况会影响疾病过程中的演变和临床结局。在癌症患者中,患者主观整体评估(PG-SGA)是评估营养状况的首选工具。本回顾性横断面研究的目的是评估 COVID-19 癌症患者治疗期间的营养状况对临床结局的影响。我们招募了 52 名正在门诊随访的癌症患者,这些患者在癌症治疗过程中被诊断患有 COVID-19。PG-SGA 工具显示,感染前的年龄( = 0.045)和营养状况( = 0.042)是 COVID-19 死亡的主要危险因素。此外,营养不良程度越高,COVID-19 导致的死亡风险越高。52 名患者中有 12 名(23.1%)未出现与 COVID-19 相关的负面影响,年龄低于 65 岁被认为是一个保护因素。