Silva Reis Bruno Fernando da, O'Dwyer Gisele, Lino Valeria Teresa Saraiva, de Oliveira Lívia Costa, da Costa Rosa Karla Santos, Sampaio Simone Garruth Dos Santos Machado
Sergio Arouca National School of Public Health, Oswaldo Cruz Foundation, Rio de Janeiro, Brazil.
Teaching Hospital of the Federal University of Pelotas, Brazilian Hospital Services Company (EBSERH), Pelotas, Brazil.
BMC Palliat Care. 2025 Jan 29;24(1):27. doi: 10.1186/s12904-025-01663-z.
To compare the sociodemographic and clinical profiles of patients with advanced cancer admitted to a tertiary palliative care unit before and during the COVID-19 pandemic.
This is an analysis of data from patients receiving care before (10/21/2019 to 03/16/2020) and during (09/23/2020 to 08/26/2021) the COVID-19 pandemic. Sociodemographic and clinical data were evaluated. Logistic regression analyses were used, with the odds ratio (OR) and 95% confidence interval (CI) as measures of effect.
673 patients were enrolled (204 in the pre-pandemic period and 469 in the pandemic period). The final logistic regression model demonstrated that patients admitted during the pandemic had a greater chance of having white skin (OR: 1.66 [95% CI: 1.15-2.39]), having a gastrointestinal tract cancer (OR: 2.95 [95% CI: 1.55-5.62]) and in skin, bones, and soft tissue (OR: 2.40 [95% CI: 1.13-5.08]), having received prior radiotherapy (OR: 1.83 [95% CI: 1.26-2.55]), and having a higher global PG-SGA SF score (OR: 1.06 [95% CI: 1.02-1.09]).
Ethnicity, nutritional risk, previous radiotherapy, and type of tumor were associated with advanced cancer during the COVID-19 pandemic. It is unclear what impacts the COVID-19 pandemic had on palliative care. This study presented findings based on one tertiary palliative care facility for patients with cancer. Give the limited literature on the subject, our comparative analysis of data serves as a starting point for a debate on this subject. More studies of a similar nature are needed to enable future comparisons and assist planning for other pandemics.
比较在新冠疫情之前和期间入住三级姑息治疗病房的晚期癌症患者的社会人口统计学和临床特征。
这是一项对在新冠疫情之前（2019年10月21日至2020年3月16日）和期间（2020年9月23日至2021年8月26日）接受治疗的患者数据的分析。对社会人口统计学和临床数据进行了评估。使用逻辑回归分析，以比值比（OR）和95%置信区间（CI）作为效应指标。
共纳入673例患者（疫情前时期204例，疫情期间469例）。最终的逻辑回归模型表明，疫情期间入院的患者有更大的几率为白种人（OR：1.66 [95% CI：1.15 - 2.39]），患有胃肠道癌症（OR：2.95 [95% CI：1.55 - 5.62]）以及皮肤、骨骼和软组织癌症（OR：2.40 [95% CI：1.13 - 5.08]），接受过先前的放疗（OR：1.83 [95% CI：1.26 - 2.55]），并且全球PG - SGA SF评分更高（OR：1.06 [95% CI：1.02 - 1.09]）。
种族、营养风险、先前的放疗以及肿瘤类型与新冠疫情期间的晚期癌症有关。目前尚不清楚新冠疫情对姑息治疗产生了何种影响。本研究基于一家针对癌症患者的三级姑息治疗机构呈现了研究结果。鉴于关于该主题的文献有限，我们对数据进行的比较分析可作为关于此主题辩论的起点。需要更多类似性质的研究以便未来进行比较并协助应对其他大流行的规划。
