INdAM Unit & Department of Information Engineering, University of Brescia, Brescia, Italy.
Department of Mathematics and Its Applications, University of Milano - Bicocca, Milan, Italy.
Acta Biotheor. 2022 Nov 15;71(1):1. doi: 10.1007/s10441-022-09452-4.
We propose a framework for the description of the effects of vaccinations on the spreading of an epidemic disease. Different vaccines can be dosed, each providing different immunization times and immunization levels. Differences due to individuals' ages are accounted for through the introduction of either a continuous age structure or a discrete set of age classes. Extensions to gender differences or to distinguish fragile individuals can also be considered. Within this setting, vaccination strategies can be simulated, tested and compared, as is explicitly described through numerical integrations.
我们提出了一个框架，用于描述疫苗接种对传染病传播的影响。不同的疫苗可以进行剂量接种，每种疫苗提供不同的免疫时间和免疫水平。通过引入连续的年龄结构或离散的年龄组来考虑个体年龄的差异。也可以考虑性别差异或区分脆弱个体的扩展。在这种情况下，可以通过数值积分明确描述来模拟、测试和比较疫苗接种策略。
