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[结痂性膀胱炎的临床诊断与治疗挑战]

[Challenges in the clinical diagnosis and treatment of encrusted cystitis].

作者信息

Gadzhiev N K, Malikiev I E, Obidnyak V M, Gorelov D S, Shkarupa D D, Gadzhieva Z K, Martov A G, Petrov S B

机构信息

Clinic for Pirogov High Medical Technologies, Saint-Petersburg, Russia.

Academician I.P. Pavlov First St. Petersburg State Medical University of the Ministry of Healthcare of Russian Federation, Saint Petersburg, Russia.

出版信息

Urologiia. 2022 Nov(5):142-146.

PMID:36382833
Abstract

Encrusted cystitis (IC) is a rare chronic inflammatory disorder of the bladder characterized by mucosal inflammation with encrustations. This pathological process is directly related to the activity of urea-splitting bacteria in the urine. Bladder encrustations are deposits of ammonium and magnesium phosphate, as well as struvite, on the surface of the urothelium. However, the pathogenesis of this disease has not been thoroughly studied. Treatment of encrusted cystitis is aimed to complete eradication of the uropathogen, surgical removal of encrustations, and lowering urine pH. Early diagnosis is a key prerequisite for effective treatment.

摘要

结痂性膀胱炎(IC)是一种罕见的膀胱慢性炎症性疾病,其特征为伴有结痂的黏膜炎症。这一病理过程与尿液中尿素分解细菌的活性直接相关。膀胱结痂是铵、磷酸镁以及鸟粪石在尿路上皮表面的沉积物。然而,该疾病的发病机制尚未得到充分研究。结痂性膀胱炎的治疗旨在彻底根除尿路病原体、手术清除结痂以及降低尿液pH值。早期诊断是有效治疗的关键前提。

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